NanoString Blog
Author: Laura Tabellini Pierre
Autoimmunity Digital Spatial Profiling Neuroscience Oncology
Readers’ Favorite Webinars: A Year in Review
NanoString webinars allow you to sit back, relax and listen to a leader in the field talk about his/her research and/or answer your questions. They have always been a crowd-pleaser,…
Digital Spatial Profiling
Redefining Precision: Why Spatial Resolution Matters
Functional annotation of gene and protein expression is a crucial step in deciphering cellular mechanisms. Traditional transcriptomic and proteomic assays are done in bulk, where RNA and proteins from different…
Neuroscience
Of Inflammasome and Tauopathies in Mice and Men
Tauopathies are a class of neurodegenerative diseases characterized by the aggregation of tau proteins in neurofibrillary tangles in the human brain. These proteins are associated to microtubules and are found…
Digital Spatial Profiling Miscellaneous
SITC 2019 may be over, but the era of Spatial Genomics enabled by the GeoMx Digital Spatial Profiler has just begun.
The curtains have fallen on SITC 2019—the 34th annual meeting organized by the Society for Immunotherapy of Cancer—but excitement amongst the participants remains high after five days of knowledge exchange…
Oncology
Immunotherapy in Tumors: Integrated Information to Outsmart Cancer
If it wasn’t such a devastating disease, there would be memes about how super-smart cancer is. Cancer cells can express neoantigens — tumor-specific, mutated peptides — that, when processed and…
Digital Spatial Profiling Miscellaneous Oncology
Meet NanoString Scientists at the AMP 2019 Annual Meeting & Expo
When Elaine Lyon, Ph.D., a scientist on the board of the Association for Molecular Pathology (AMP) was asked why she is involved with AMP, its activities and initiatives, she quoted…
Oncology
Top Challenges of Biofluid Samples when Profiling FFPE miRNA Biomarkers
In 1993, Dr. Victor Ambros’ lab discovered a small RNA sequence, Lin-4, that was “essential for the normal temporal control of diverse postembryonic developmental events in C. Elegans”. Sequence analysis…
Oncology
The bench side of organ transplant: Challenges and solutions
“It is infinitely better to transplant a heart than bury it to be devoured by worms,” said Dr. Christiaan Barnard, the father of the heart transplant. It’s hard to disagree…
Digital Spatial Profiling Miscellaneous
A day (or two) with the Experts: the 2019 EU NanoString Summits Crosstalk
Since 2017 NanoString has hosted day-long summits in some of the liveliest and most charming European locations, where scientists and key opinion leaders have had the opportunity to share with…
Oncology
Aiming at the Achilles’ heel of cancer: multiplexed lung cancer fusion detection without FISH or NGS
Lung cancer is the most commonly diagnosed cancer worldwide, and the leading cause of cancer deaths in the United States. It is generally divided into two types, non-small cell lung…
Autoimmunity Immunology
How to Resolve the Complexity of Autoimmune Diseases
What are Autoimmune Diseases? Autoimmune diseases are chronic inflammatory conditions, life-long debilitating illnesses with increased mortality, and high healthcare costs for therapy and care. They are systemic conditions characterized by…
Oncology
miRNA Profiling in Malignant Melanoma: Making “Australia’s National Cancer” Obsolete.
Australia is a sun-worshipping country, the world capital for beautiful beaches, athletic surfers, cute marsupials, and the occasional weird-looking animal. But it is also the capital for something less pleasant:…