Vantage 3D™ Assays
Helping Your Research
NanoString is pioneering the field of 3D Biology to accelerate the rate of research and maximize the amount of information that can be generated from a single sample. 3D Biology™ Technology is the ability to analyze combinations of RNA and protein simultaneously in a single experiment. Based on the NanoString digital barcode technology and designed for flexibility, the nCounter Vantage 3D Portfolio of assays provides a deeper view of cancer and immune biology and can be mixed and matched to answer a wide variety of biological questions.
How It Works
The nCounter Vantage 3D portfolio is designed for flexibility. Each panel can also be run as a stand-alone assay so you can generate the data you need. Select the right targeted panels for each analyte type, and detect and analyze them all at once with the nCounter Analysis System and nSolver™ software.
With the Vantage 3D portfolio, you can mix and match content based on your research needs with multi-analyte assays for Immuno-Oncology and Solid and Heme Tumor Profiling.
Panel Selection Tool
Find the gene expression panel for your research with easy to use panel proFind Your Panel
Vantage 3D RNA Panels
Vantage 3D Fusion Panels
Vantage 3D Protein Panels
Panel Compatibility and Customization
Each panel can be run as a stand-alone assay with customization available. Up to 24 user- defined genes can be added to any Vantage 3D RNA panel, including fusion panels. Up to five custom protein targets can be added to any Vantage 3D Protein panel using the Protein Barcoding Service.
Unsure if you can perform your desired experiment in a single lane? The table below provides an overview of analyte compatibility:
Digital Spatial Profiling Reveals Functional Shift of Enterochromaffin Cell in Patients With Ulcerative Colitis.
As a major component of the enteroendocrine system, enterochromaffin (EC) cells play a key role in ulcerative colitis (UC). However, the scarcity of EC cells has limited the investigation of their function.
PSMA-targeting TGFbeta-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial.
Chimeric antigen receptor (CAR) T cells have demonstrated promising efficacy, particularly in hematologic malignancies. One challenge regarding CAR T cells in solid tumors is the immunosuppressive tumor microenvironment (TME), characterized by high levels of multiple inhibitory factors, including transforming growth factor (TGF)-beta.
Immunostimulatory cancer-associated fibroblast subpopulations can predict immunotherapy response in head and neck cancer.
Purpose: Cancer-associated fibroblasts (CAF) have been implicated as potential mediators of checkpoint immunotherapy response. However, the extensive heterogeneity of these cells has precluded rigorous understanding of their immunoregulatory role in the tumor microenvironment.