What is the Spatial Tissue Book?
The Spatial Tissue Book is a repository of images, data, selection and segmentation strategies for different tissue types and diseases that have been analyzed through either the GeoMx® DSP Technology Access Program or the CosMx™ SMI Technology Access Program.
Each individual PDF page of the Tissue Book includes images of the tissue and is annotated by the disease(s) studied, species of interest, and type of assay performed.
Why Use the Tissue Book?
- See representative images for tissues and/or disease areas that you are studying.
- Get ideas on how to select ROIs and segment the tissue to meet your study design needs.
- Review spatial transcriptomics data from different tissues representing various diseases.
Explore the anatomy of a GeoMx tissue book page
The type of tissue and disease profiled.
Learn about the application and study design.
Get a high-level overview of what kind of sample type was used, species, strategy for area of illumination as well as the assay and morphology markers used. Learn how many targets were detected from the assay for this particular study.
See an actual image taken with either the GeoMx Digital Spatial Profiler or the CosMx Spatial Molecular Imager annotated with the different fluorescent markers used to outline tissue morphology and/or cell types.
Learn more about the Segmentation Strategy and how individual regions of interest were compartmentalized into different areas of illumination and/or cell type populations.
See how many targets were detected above the background for each tissue compartment and/or cell type profiled.
View additional plots showing the results of the study.
Here you can click on this link to visit our Morphology Marker page to learn about which fluorescently-tagged antibodies or RNAScope Probes have been used on the GeoMx DSP.
The CosMx™ SMI and decoder probes are not offered and/or delivered to the Federal Republic of Germany for use in the Federal Republic of Germany for the detection of cellular RNA, messenger RNA, microRNA, ribosomal RNA and any combinations thereof in a method used in fluorescence in situ hybridization for detecting a plurality of analytes in a sample without the consent of the President and Fellows of Harvard College (Harvard Corporation) as owner of the German part of EP 2 794 928 B1. The use for the detection of cellular RNA, messenger RNA, microRNA, ribosomal RNA and any combinations thereof is prohibited without the consent of the President and Fellows of Harvard College (Harvard Corporation).
The CosMx™ SMI and decoder probes are not offered and/or delivered to the following UPC member states* for use in these countries for the detection of RNA in a method used for the detection of a plurality of analytes in a cell or tissue sample without the consent of the President and Fellows of Harvard College (Harvard Corporation) as owner of the Unitary Patent EP 4 108 782 B1. The use for the detection of RNA is prohibited without the consent of the President and Fellows of Harvard College (Harvard Corporation).
* Austria, Belgium, Bulgaria, Denmark, Estonia, Finland, France, Germany, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Portugal, Slovenia, Sweden
Tissue Book Collection
Browse entries here, or just download the complete tissue book.
|Lung||NSCLC||Human||FFPE||1000-Plex Human RNA Universal Cell Characterization||CosMx||Download|
|Liver||Normal||Human||FFPE||1000-Plex Human RNA Universal Cell Characterization||CosMx||Download|
|Liver||Hepatocellular Carcinoma||Human||FFPE||1000-Plex Human RNA Universal Cell Characterization||CosMx||Download|
|Brain||Normal||Mouse||Fresh Frozen||CosMx Mouse Neuroscience Panel||CosMx||Download|
|Breast||Breast Cancer||Human||FFPE||1000-Plex Human RNA Universal Cell Characterization||CosMx||Download|
|Kidney||Pediatric Renal Allograft||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Lymph Node||Lymphoma||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Lung||Lung Cancer||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Skin||Hidradenitis Suppurativa||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Brain||Parkinson's Disease||Mouse||FFPE||Mouse Whole Transcriptome Atlas||GeoMx||Download|
|Ovary||Ovarian Cancer||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Brain||Schizophrenia||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Breast||Breast Cancer||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Colon||Colonic Adenoma||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Esophagus||Barrett's Mucosa||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Kidney||Kidney Cancer||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Liver||Hepatocellular Carcinoma||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Lung||COVID-19||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Lung||Tuberculosis||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Lung||NSCLC||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Muscle||Myositis||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Placenta||Chronic Intervillositis of Unknown Etiology||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Prostate||Prostate Cancer||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|
|Skin||Melanoma||Human||FFPE||Human Whole Transcriptome Atlas||GeoMx||Download|