Propath: An nCounter® Grant Open to all Pharma, Biotech and Academic Research Applicants
Grant Closes Friday, March 11
NanoString is Partnering with Propath UK a Specialist in Molecular Pathology to Perform the Sample Analysis in the ADC Panel Grant
Streamline your ADC sample analysis by combining information from multiple assays into a single NanoString gene expression panel
Save time and reduce the number of assays required to generate biologically-relevant data!
The nCounter® Antibody Drug Conjugate (ADC) panel was designed for various sample types that are collected across the full drug development spectrum from process development to clinical trial sample analysis. NanoString’s new ADC Panel is a unique research tool specifically designed to enable the success of ADC development through each stage of these processes. Measure six distinct stages of ADC delivery and response in a single gene expression panel, enabling you to gauge the success of chemotherapy and combination immunotherapy drug development programs.
Answer all the questions you really want to address in ADC R&D, preclinical, and clinical studies
- Leverage the wide range of cancer antigen expression targets
- ~100 pan-cancer antigen targets for a wide range of applicability
- Simultaneously evaluate ADC cell absorption & payload release
- endocytosis & related lysosomal pathways analysis
- antibody-linker-payload separation analysis
- Evaluate drug MOA & toxicity
- intentional effects of cytotoxic agents
- cellular stress pathways
- bystander effects
- Perform a deep dive into immune synergies
- immunomodulatory pathway analysis
- NanoString partners with Propath UK, a specialized molecular pathology nCounter and DSP CRO Service Provider to award the most impactful proposal with the ability to accelerate ADC programs
- A 12 sample analysis study including Advanced Analysis through nSolver software
- R&D, process development, preclinical, clinical samples
- Need some help? Contact us to speak to our in-house experts before you submit your project application.
Propath UK is a specialist CRO providing research services in molecular pathology, spatial biology and histopathology for the global biopharmaceutical sector. We offer a range of platforms for spatial and transcriptomic analysis, including the NanoString GeoMx and NanoString nCounter and, most recently, the Lunaphore Comet for hyper-plex IHC analysis. Our reputation has been gained over the past 40 years by providing a consistent and responsive service across thousands of pre-clinical and clinical studies. Visit www.propath.co.uk to learn more about our services or to contact us.
* Should you require analysis of more than 12 samples please contact Propath UK
Terms and Conditions
Participation in the Propath NanoString grant programme is open to all those who meet these eligibility requirements. Entrants must be professionally engaged in laboratory-based scientific research, have attained at least the age of majority in their jurisdiction of residence (entrants must, in any event, be at least 18 years of age), and be able to provide the samples within 45-60 days of notification. Employees, officers, directors, agents, representatives and independent contractors of the Sponsors, its subsidiaries or affiliated companies, together with their immediate family members and members of the same households (whether related or not) are not eligible to participate. Also ineligible are any persons for whom it would be illegal to participate in or win the scientific challenge, or with or to whom it would be illegal for the Sponsors to interact or award the Grant as contemplated herein. No purchase is necessary. The Grant is subject to all applicable laws and regulations, and is void where prohibited or where registration, bonding or language translation is required.
HOW TO ENTER
The application period begins on February 1 at 12:01 a.m. (BST) and ends on March 11, 2022 at 11:59 p.m. (BST); entries must be submitted during that period to be eligible. To enter, participants must submit a short abstract application. The application must include: (1) the participant’s full name, email address, telephone number and any other contact information required by the Sponsors; (2) the name of the participant’s institution or company; (3) a descriptive title for the proposed project; (4) an abstract proposal (written in 500 words or less) demonstrating how NanoString nCounter will aid in interrogating your samples and how that will fuel discovery in your field of research; and 5) include statement on the availability of RNA samples for use in your project (for example, please state whether the samples are in your possession/accessible from collaborators/biobanks/repositories, and whether appropriate consent/IRB approval is in place). By entering, the participant gives permission to the Sponsors to contact the participant regarding the Sponsors’ products and services, whether or not the participant is chosen as the winner. Each participant shall be entitled to make one (1) entry into the Grant only. In the event that the Sponsors deem a participant to have made multiple applications to enter or to have acted in bad faith with respect to the Grant, the participant shall be excluded from the Grant and consequently ineligible to win the grant, as defined below.
SELECTION OF WINNERS AND NOTIFICATION
Two winners will be selected from all qualified applications by a panel of the Sponsors’ scientists, who will choose the application that, in the sole discretion of the Sponsors, best makes use of the grant to demonstrate the power of NanoString’s nCounter Technology.
Selection Criteria will include but are not limited to: 1) novelty and impact on research field of interest; 2) sample availability; 3) well-defined and publishable end points; and 4) ability for RNA samples to be provided to Propath by April 1, 2022.
The decision of this panel will be final and binding and shall not be subject to review or appeal by any participant or by any third party. The selected winners will be attempted to be notified by email within approximately five (5) business days after selection. If the selected winner has not responded to email inquiries within three (3) days, the Sponsors will attempt to contact the winner by telephone. If the winner cannot be reached by telephone within forty-eight (48) hours of first telephone attempt to notify such winner, the grant may be forfeited, and an alternate winner selected, based on the criteria set forth above, at the Sponsors’ discretion. The odds of winning depend on the number of eligible entries received.
GRANT DESCRIPTION & CONSUMER DISCLOSURE
The winner of the grant will receive wet lab and bioinformatic support for processing of up to 12 RNA samples on the NanoString nCounter platform. Any of the commercially available Assays listed on the Application form can be used for this analysis. An assay report, including raw data and processed results, will be provided to the winner(s). All work performed is for Research Use Only.
PUBLICATION OF PROJECT RESULTS:
All grant submissions are confidential to the individual submitter and will not be published or distributed. Upon project completion, each grant winner agrees to participate in at least one of the following activities relating to the specific project, with specific details of the applicable activity to be mutually agreed upon in good faith by Propath and the winner: webinar, case study, or poster presentation. Each winner agrees that Propath and NanoString shall have the right to publicly announce the winner’s name and research topic and use anonymized data from the winner’s project in application notes including in marketing materials and seminars.
The grant may not be transferred or assigned; no substitutions or cash equivalents are allowed. The winner may be required to execute and return an affidavit of eligibility/release of liability/publicity release (where legal) within twenty-one (21) days of first notification attempt. If the winner fails to return the affidavit/release by the deadline, the grant will be forfeit and an alternate winner may be selected, based on the criteria set forth above, at the Sponsors’ discretion. The participant understands and agrees that no ideas, information or materials that are submitted to or otherwise provided to the Sponsors in connection with the Grant will be returned, and that the Sponsors make no guarantee or warranty with respect to the security or confidentiality thereof. All taxes on the grant and reporting thereof, and any other costs, fees and expenses relating to the grant or the scientific challenge, are the sole responsibility of the winner and/or the winner’s institution or company. By submitting an application or accepting the grant, the participant agrees on behalf of the participant and the participant’s institution or company: (1) to be bound by these official rules; (2) that the Sponsors shall retain full authority, in their sole discretion, to interpret and administer these rules; (3) that any dispute with regard to the conduct of the Grant, rule interpretation or award of the grant, shall be resolved by the Sponsors, whose decision shall be binding and final; (4) to be bound by all decisions and interpretations made in good faith by the Sponsors; and 5) that all use of NanoString’s products will be subject to NanoString standard terms and conditions of sale. Furthermore, the participant represents and warrants that: (1) the participant meets the eligibility requirements of the Grant; (2) the participant has obtained all required authorizations and permissions from the participant’s institution or company; (3) entering into the Grant Program does not and will not violate any law or regulation, or any of the institution’s or company’s rules or policies; and (4) the information contained in the application is true and correct in all material respects and is owned or rightfully possessed by the participant without restriction on disclosure. The Sponsors may refuse to award the grant if the Sponsors determine in their sole discretion that doing so would likely result in a violation of an applicable law, rule, or policy.
USE OF WINNER’S NAME
The participant acknowledges and agrees that, if the participant is selected as the winner, the participant’s name, biographical information, likeness, the name of the participant’s institution or company and the project title (excluding further project details) may, without further compensation, be published on one or more Sponsor website(s) and, at the Sponsors’ discretion, through social media. By accepting the grant, the winner grants to the Sponsors, on behalf of the winner and the winner’s institution or company, the right, at any time and from time to time, to print, publish, broadcast and use, worldwide and in any media now known or hereafter developed (including, but not limited to, social media, the Internet and the world wide web), the winning participant’s name, biographical information, (if provided by the participant) image, likeness, the name of the winning participant’s institution or company and the project title (excluding further project details).
INDEMNITY, DISCLAIMER & LIMITATION OF LIABILITY
By participating in the Grant, the participant agrees on behalf of the participant and the participant’s institution or company to release, discharge, indemnify and hold harmless the Sponsors and their respective affiliates, subsidiaries, officers, directors, employees, agents and representatives from all liability for any injury, loss or damage, including death or property damage, due in whole or part, directly or indirectly, to the participation in the Grant or the acceptance, possession, use or misuse of the grant. The Sponsors have not made any warranty, representation, or guarantee, express or implied, in fact or in law, with respect to the grant, including, without limitation, to such grant’s quality or fitness for a particular purpose.
THE SPONSORS ARE NOT RESPONSIBLE FOR LOST, LATE, STOLEN, INCOMPLETE, ILLEGIBLE, INACCURATE, UNDELIVERED, DELAYED OR MISDIRECTED ENTRIES, OR FOR ANY COMPUTER, THE INTERNET, EMAIL, TELEPHONE OR TECHNICAL MALFUNCTIONS OR DELAYS, OR FOR ANY HUMAN ERRORS THAT OCCUR IN THE PROCESSING, TRANSMISSION OR RECEIPT OF ENTRIES, OR FOR INACCURATE TRANSCRIPTION OF ENTRY INFORMATION, OR IF THE SCIENTIFIC CHALLENGE IS NOT CAPABLE OF BEING CONDUCTED AS PLANNED, INCLUDING BUT NOT LIMITED TO INFECTION BY COMPUTER VIRUSES, BUGS, TAMPERING, UNAUTHORIZED INTERVENTION, FRAUD, TECHNICAL FAILURES, OR OTHER CAUSES BEYOND THE CONTROL OF THE SPONSORS. IN NO EVENT SHALL THE SPONSORS OR THEIR RESPECTIVE AFFILIATES, SUBSIDIARIES, OFFICERS, DIRECTORS, EMPLOYEES, AGENTS OR REPRESENTATIVES BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, CONSEQUENTIAL, SPECIAL, EXEMPLARY OR PUNITIVE DAMAGES WHATSOEVER ARISING OUT OF OR IN CONJUNCTION WITH PARTICIPATION IN THE GRANT OR THE ACCEPTANCE, POSSESSION, USE OR MISUSE OF THE GRANT, WHETHER BASED ON WARRANTY, CONTRACT, TORT, STRICT LIABILITY, OR ANY OTHER LEGAL THEORY, AND WHETHER OR NOT ANY OF THEM ARE ADVISED OF THE POSSIBILITY OF SUCH DAMAGES. THE FOREGOING LIMITATION OF LIABILITY SHALL APPLY TO THE FULLEST EXTENT PERMITTED BY LAW. THE SPONSORS’ TOTAL AND CUMULATIVE LIABILITY ARISING OUT OF OR IN CONNECTION WITH THE DSP GRANT SHALL IN NO EVENT EXCEED THE TOTAL VALUE OF THE GRANT.
The Sponsors reserve the right to suspend, modify, cancel or terminate the Grant without advance notice, including, without limitation, in the event of any act, occurrence or reason that it believes would compromise the legality, integrity, administration or fairness of the Grant. If one or more provisions of these official rules are held to be invalid or unenforceable by a court of competent jurisdiction, the remaining provisions shall be valid and enforceable. Any dispute or claim arising out of or in connection with it or its subject matter or formation (including non-contractual disputes or claims), shall be governed by, and construed in accordance with, English law, and the parties irrevocably submit to the exclusive jurisdiction of the courts of England. The failure of the Sponsors to comply with any provision of these official rules due to civil unrest, threat of or actual acts of terrorism or war, embargoes, governmental actions, acts of God, earthquakes, floods, storms, fires, supplier delay, accidents, explosions, epidemics, quarantine restrictions, or other such contingencies beyond the control of the Sponsors, shall not be considered a breach of these rules. The Sponsor of this programme is Propath UK Limited of registered address Willow Court, Netherwood Road, Hereford, HR2 6JU.