OLD Category: GeoMx DSP

Single-cell and spatial analyses of cancer cells: toward elucidating the molecular mechanisms of clonal evolution and drug resistance acquisition

• Nagasawa S, Kashima Y, Suzuki A, Suzuki Y

The Potential of OMICs Technologies for the Treatment of Immune-Mediated Inflammatory Diseases

• Anchang CG, Xu C, Raimondo MG, Atreya R, Maier A, Schett G, Zaburdaev V, Rauber S, Ramming A

Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1

• Lu Y, Ng AHC, Chow FE, Everson RG, Helmink BA, Tetzlaff MT, Thakur R, Wargo JA, Cloughesy TF, Prins RM, Heath JR

A Distinct Innate Immune Signature of Early Onset Colorectal Cancer

• Gardner IH, Siddharthan R, Watson K, Dewey E, Ruhl R, Khou S, Guan X, Xia Z, Tsikitis VL, Anand S

Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer

• Roper N, Velez MJ, Chiappori A, Kim YS, Wei JS, Sindiri S, Takahashi N, Mulford D, Kumar S, Ylaya K, Trindade C, Manukyan I, Brown AL, Trepel JB, Lee JM, Hewitt S, Khan J, Thomas A

Spatial transcriptomics and proteomics technologies for deconvoluting the tumor microenvironment

• Wang N, Li X, Wang R, Ding Z

Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids

• Koh V, Chakrabarti J, Torvund M, Steele N, Hawkins JA, Ito Y, Wang J, Helmrath MA, Merchant JL, Ahmed S, Shabbir A, Bok Yan So J, Yong WP, Zavros Y

Models that combine transcriptomic with spatial protein information exceed the predictive value for either single modality

• Vathiotis IA, Yang Z, Reeves J, Toki M, Aung TN, Wong P, Kluger H, Syrigos KN, Warren S, Rimm DL

Cutaneous Melanoma Classification: The Importance of High-Throughput Genomic Technologies

• Scatena C, Murtas D, Tomei S

Multiplexed digital spatial profiling of invasive breast tumors from Black and White women

• Omilian AR, Sheng H, Hong CC, Bandera EV, Khoury T, Ambrosone CB, Yao S.

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

• Delorey TM, Ziegler CGK, Heimberg G...Villani AC, Rozenblatt-Rosen O, Regev A

Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response

• McNamara KL, Caswell-Jin, JL, Joshi R, Ma Z, Kotler E, Bean GR, Kriner M, Zhou Z, Hoang M, Beechem J, Zoeller J, Press MF, Slamon DJ, Hurvitz SA, Curtis C