CosMx™ SMI
Best Practices
Harness the potential of single-cell spatial
We’re unveiling a compilation of expert tips aimed at optimizing your CosMx™ SMI spatial runs, ensuring researchers harness the full potential of their instruments effortlessly. Be sure to revisit frequently as we continuously enhance this repository of invaluable best practices.
Volume I: CosMx 1000-plex RNA Assays: Considerations When Generating Single-Cell Spatial Data
- Tip 1: Interpret Data by Tissue and Disease Type
- Tip 2: Consider Sample Preparation Conditions
- Tip 3: Plan Instrument Run Conditions
Volume II: Tips When Generating Single-Cell Spatial Data: Sample Selection
- Protocol Updates
- Tip 1: Evaluate Tissue Block Quality
- Tip 2: Evaluate Tissue Section Quality
- Tip 3: Consider Tissue Heterogeneity and Autofluorescence
Volume III: Tips when Generating Single-Cell Spatial Data: Post Run H&E and Antibody Staining