NanoString Blog

CosMx tissue image


Tips when Generating Single-Cell Spatial Data: Post Run H&E and Antibody Staining

We are excited to share the third installment of tips for successful CosMx™ SMI single-cell spatial runs at 1000-plex. Our first installment of tips focused on data by tissue and…

NanoString / May 9, 2024
CosMx tissue image


Tips When Generating Single-Cell Spatial Data: Sample Selection 

We are excited to share the second installment of tips for successful CosMx™ SMI single-cell spatial runs at 1000-plex. Our first installment of tips focused on data by tissue and…

NanoString / February 13, 2024

Spatial Biology

NanoString Powered by NVIDIA GPU Technology Accelerates Scientific Discovery and the Age of Spatial Biology

For researchers studying diseases that cruelly take the lives of millions — Alzheimer’s disease, lung, colon, breast, and pancreatic cancer, among others — it has been a long-held dream to…

Sriya Malladi and Meg O'Conor / January 9, 2024
CosMx tissue image


Top 3 Tips for Successful CosMx™ SMI Single-cell Spatial Runs at 1000 plex

We are excited to share insights and recommendations to enhance your experience with CosMx™ SMI 1000-plex RNA assays. The quality of single-cell spatial data is influenced by various factors, and…

NanoString / December 13, 2023
Geo location


Getting Started with Your First GeoMx® DSP Experiment: A Step-by-Step Guide

The GeoMx Digital Spatial Profiler (DSP) is a powerful tool for spatial multiomics, the in situ analysis of RNA and protein expression in tissue sections. GeoMx DSP gives you the…

Elizabeth Schneider / December 11, 2023
Rendering of oncology proteins

nCounter Oncology

GEP Signatures Unleashed: The LST for Diffused Large B-Cell Lymphoma, DLBCL, Subtyping and Its Expanding Applications

Gene expression profiling (GEP) signatures, comprising sets of genes characteristic of specific diseases, tissues, cell types, cell states, or biological perturbation, hold significant diagnostic, predictive, and prognostic value, positioning them…

Espy Anguiano / October 31, 2023

CosMx SMI Spatial Biology

Complex Cell Segmentation and Its Significance in Spatial Biology

In research, scientists are continually pushing boundaries to gain deeper insights into biology, medicine, and drug discovery. Single-cell spatial imaging has emerged as a powerful technology in the field of…

Lisa Kessler / October 30, 2023
Oncology protein rendering

Immunology nCounter Oncology

TIS GEP: Use Cases in Sample Stratification, Assessment of Treatment Effect, and as a Component of a Multivariate Biomarker

Introduction to the TIS Gene Expression Profile Innovations in multiplex gene expression analysis are revolutionizing translational research and clinical practices by enabling identification of gene signatures involved in various biological…

Espy Anguiano / October 10, 2023

Multiomics Spatial Analysis Spatial Biology Spatial Transcriptomics

GeoMx® DSP Spatial Proteogenomics datasets now available on Illumina® BaseSpace™ Sequence Hub

NanoString and Illumina have collaborated to release two new demo datasets of GeoMx Digital Spatial Profiler (DSP) data on the Illumina BaseSpace Sequence Hub (BSSH) cloud.  Spatial proteogenomics enables new…

Megan Vandenberg, Margaret Hoang and Sophie Wehrkamp-Richter / September 14, 2023
PAM50 GEP Signature A medical female worker is holding a pill.


Utility of PAM50 GEP Signature as a Biomarker for Exploratory Endpoints in Drug Discovery and Development

The Need for Gene Expression Profiling Gene expression profiling has emerged as a genomic tool that can help decipher the complexity of cancer subtyping. Conceptually, cancer is a fairly simple…

Espy Anguiano / August 9, 2023

Spatial Biology

Why is the human proteome important?

The Human Protein Atlas is one of the world’s largest biological databases, containing spatial expression profiles for all known proteins expressed in human organs and tissues. It contains a vast…

Nirupama Deshpande / July 7, 2023

Spatial Biology

What are immunofluorescence techniques?

Tissue and cell samples constitute the main source of samples for protein or RNA expression analysis in biology and help us understand how cells interact, organize themselves, and drive various…

Nirupama Deshpande / July 6, 2023