GeoMx® Protein Assays
High-plex Spatial Proteomics Made Easy
GeoMx® DSP Protein Assays enable quantitative, spatial analysis of up to 570+ proteins from a single FFPE or fresh frozen tissue section, vastly expanding the number of markers you can profile from a single tissue section compared to traditional immunohistochemical methods. All assays are validated for use in multiplex so you can spend more time discovering new biology and less time troubleshooting assay performance.
Each assay is made up of IHC-compatible antibodies coupled to photocleavable oligonucleotide barcodes designed for readout with either the nCounter® Analysis System or via next-generation sequencing (NGS) using an Illumina system. After hybridization of antibodies to tissue sections, the barcodes are released from discrete regions of interest (ROIs) on the tissue via exposure to UV light. Released tags are counted and mapped back to tissue location, yielding a spatially resolved digital profile of protein expression.
GeoMx® Immuno-Oncology Protein Panels
Built with a modular design to provide flexible and comprehensive coverage of the tumor and tumor microenvironment, profile up to 96 curated protein targets…
GeoMx® Neuroscience Protein Panels
With comprehensive coverage of key neural cell types and neurodegenerative disease pathology, profile curated protein targets with spatial resolution…