Cell & Gene Therapy Solutions

CAR-T • Stem Cell • Gene Therapy

Identifying Needs • Navigating Challenges • Creating Novel Solutions

Cell & Gene Therapies (CGTs) are a transformative class of medicines addressing treatment needs for cancer, rare diseases, neurodegenerative diseases and regenerative medicine just to name a few and include a broad range of approaches including CAR-T Cell Therapy, Stem Cells and Gene Therapies. Although CGTs have made a significant positive impact on healthcare, scientists are still facing marked challenges at every step of the process. Join NanoString as we address the important needs and challenges throughout Discovery, Biomanufacturing and Clinical Trials.

Challenges

Understanding the myriad of complex challenges including those that fall outside of the scientific realm and taking on each challenge methodically is necessary to bring speed and efficiency to the process.

illustration of a stopwatch

Time to Results

Arrow in target

Quality & Consistency

Balls and arrow

Assay Modernization

Two documents

Regulatory Compliance

Product Functionality & Efficacy

Triangular warning sign

Dosing/Safety/Toxicity

Molecule

Biomarker Identification

NanoString’s three platform solutions and standardized panels bring unlimited potential for your CGT work with CAR-T, Stem Cells or Gene Therapy.

Modernize Testing

  • Improve time to results
  • Characterize early and concurrently throughout drug development.
  • Consolidate & customize assays

Improve Product Quality

  • Achieve consistent in-process results
  • Design manufacturing efficiencies for speed
  • Develop menu of assays using reliable platform
  • Fully automated workflow

Characterize Manufacturing Upstream and Downstream

  • Identify the right drug target & candidate
  • Discover biomarkers of response, and safety
  • Accurately measure biodistribution and MOA with spatial platforms

Novel Applications

  • Biodistribution
  • Biomarker discovery
  • Treatment response
  • Toxicity and safety
  • Transfection efficacy
  • Receptor-ligand and cell-cell interactions
  • Phenotyping
  • Transgene detection in cellular and subcellular context

nCounter Panels for Molecular Characterization

Three Platforms. Unlimited Potential.

Whether you’re characterizing with standard gene expression or exploring with novel spatial biology approaches, NanoString’s platforms and integrated analytics provide robust and reproducible technologies to bring progress to your work.

Head-on view of the nCounter Pro instrument
nCounter Pro® Analysis System
Head-on view of the GeoMx instrument
GeoMx® Digital Spatial Profiler
Head-on view of the CosMx instrument
CosMx™ Spatial Molecular Imager

Why Use nCounter Pro for Biomanufacturing?

  • Perform scalable translational studies for biomarker development, biodistribution, drug efficacy, and to safety monitor risk assessments
  • Apply novel spatial translational tools for biomarker discovery for all areas and stages of CGT drug development including evaluation of pre-clinical and clinical patient responses

Why Innovate Your CGT Research with Spatial Solutions?

  • Consolidate and customize assays using a simple assay workflow that addresses complex analytical needs
  • Generate highly robust data within 24 hours with any sample input to accelerate time to results
  • Perform analysis under a 21CFR Part 11 compliant platform

Learn More

Find out more about our comprehensive solutions for CGT

Cell & Gene Therapy Solutions Brochure

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Related Resources

Brochure Cell & Gene Therapy Solutions Brochure
Infographic Cell & Gene Therapy Solutions Infographic