OLD Category: immuno-oncology

The Use of a Humanized NSG-β2m−/− Model for Investigation of Immune and Anti-tumor Effects Mediated by the Bifunctional Immunotherapeutic Bintrafusp Alfa

• Morillon YMI et al.,

An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer

• Tsakonas G et al.,

Spatially-resolved Quantification of Proteins in Triple Negative Breast Cancers Reveals Differences in the Immune Microenvironment Associated With Prognosis

• Stewart RL, Matynia AP, Factor RE, Varley KE.

Functional and mechanistic advantage of the use of a bifunctional anti-PD-L1/IL-15 superagonist

• Knudson KM, Hicks KC, Ozawa Y, Schlom J, Gameiro SR

Inhibition of the Wnt/β-catenin pathway enhances antitumor immunity in ovarian cancer

• Doo DW et al.,

Adrenergic stress constrains the development of anti-tumor immunity and abscopal responses following local radiation

• Chen M et al.,

Changing Technologies of RNA Sequencing and Their Applications in Clinical Oncology

• Wang Y, Mashock M, Tong Z, Mu X, Chen H, Zhou X, Zhang H, Zhao G, Liu B, Li X

Assessment of the Feasibility and Safety of Durvalumab for Treatment of Solid Tumors in Patients With HIV-1 Infection: The Phase 2 DURVAST Study

• Gonzalez-Cao M et al.,

LAG3: a novel immune checkpoint expressed by multiple lymphocyte subsets in diffuse large B-cell lymphoma

• Keane C, Law SC, Gould C, Birch S, Sabdia MB, Merida de Long L, Thillaiyampalam G, Abro E, Tobin JW, Tan X, Xu-Monette ZY, Young KH, Gifford G, Gabreilli S, Stevenson WS, Gill A, Talaulikar D, Jain S, Hernandez A, Halliday SJ, Bird R, Cross D, Hertzberg M, Gandhi MK

Early hepatic lesions display immature tertiary lymphoid structures and show elevated expression of immune inhibitory and immunosuppressive molecules

• Meylan M et al.,

Digital quantitative assessment of PD-L1 using digital spatial profiling

• Gupta S, Zugazagoitia J, Martinez-Morilla S, Fuhrman K, Rimm DL

Biomarkers associated with beneficial PD-1 checkpoint blockade in non-small-cell lung cancer (NSCLC) identified using high-plex digital spatial profiling

• Zugazagoitia J, Gupta S, Liu Y, Fuhrman K, Gettinger S, Herbst RS, Schalper KA, Rimm DL.