OLD Category: Oncology

Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy

• Liu WN, Fong SY, Tan WWS, Tan SY, Liu M, Cheng JY, Lim S, Suteja L, Huang EK, Chan JKY, Iyer NG, Yeong JPS, Lim DW, Chen Q.

Cyclophilin A inhibitor Debio-025 targets Crk, reduces metastasis, and induces tumor immunogenicity in breast cancer

• Davra V et al.,

Myeloid cell-derived TGF-beta signaling regulates ECM deposition in mammary carcinoma via adenosine-dependent mechanisms

• Vasiukov G, Novitskaya T, Zijlstra A, Owens P, Ye F, Zhao Z, Moses HL, Blackwell T, Feoktistov I, Novitskiy SV

The Use of a Humanized NSG-β2m−/− Model for Investigation of Immune and Anti-tumor Effects Mediated by the Bifunctional Immunotherapeutic Bintrafusp Alfa

• Morillon YMI et al.,

Spatiotemporal regulation of ΔNp63 by TGFβ-regulated miRNAs is essential for cancer metastasis

• Bui NHB, Napoli M, Davis AJ, Abbas HA, Rajapakshe K, Coarfa C, Flores ER

An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer

• Tsakonas G et al.,

Spatially-resolved Quantification of Proteins in Triple Negative Breast Cancers Reveals Differences in the Immune Microenvironment Associated With Prognosis

• Stewart RL, Matynia AP, Factor RE, Varley KE.

MicroRNA Expression Profiling of Normal and Malignant Human Colonic Stem Cells Identifies miRNA92a as a Regulator of the LRIG1 Stem Cell Gene

• Viswanathan V et al.,

Functional and mechanistic advantage of the use of a bifunctional anti-PD-L1/IL-15 superagonist

• Knudson KM, Hicks KC, Ozawa Y, Schlom J, Gameiro SR

Microarray data analysis on gene and miRNA expression to identify biomarkers in non-small cell lung cancer

• Jin X et al.,

Multiplexed evaluation of microdosed antineoplastic agents in situ in the tumor microenvironment of patients with soft tissue sarcoma

• Gundle KR, Deutsch GB, Goodman HJ, Pollack SM, Thompson MJ, Davis JL, Lee MY, Ramirez DC, Kerwin W, Bertout JA, Grenley MO, Sottero KHW, Beirne E, Frazier J, Dey J, Ellison M, Klinghoffer RA, Maki RG

Distinct gene expression profiles associated with clinical outcomes in patients with ovarian clear cell carcinoma and high-grade serous ovarian carcinoma

• Zhou H et al.,