OLD Category: regulatory biology

cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE

• Motwani M, McGowan J, Antonovitch J, Gao KM, Jiang Z, Sharma S, Baltus GA, Nickerson KM, Marshak-Rothstein A, Fitzgerald KA

Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung

• Liu H, Xu W, Bruno VM...Bromley MJ, Mitchell AP, Filler SG

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome

• Inak G, Rybak-Wolf A, Lisowski P...Rajewsky N, Schuelke M, Prigione A

Cancer-associated fibroblasts activated by miR-196a promote the migration and invasion of lung cancer cells

• Lee S, Hong JH, Kim JS...Lee Kang J, Ko YH, Ahn YH

GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling

• Pulsipher A, Savage JR, Kennedy TP, Gupta K, Cuiffo BG, Sonis ST, Lee WY

Regulation of splenic monocyte homeostasis and function by gut microbial products

• Kolypetri P, Liu S, Cox LM, Fujiwara M, Raheja R, Ghitza D, Song A, Daatselaar D, Willocq V, Weiner HL

Evaluating a New Class of AKT/mTOR Activators for HIV Latency-Reversing Activity Ex Vivo and In Vivo

• Gramatica A, Schwarzer R, Brantley W...Pillai SK, Okoye AA, Greene WC

Chronic adrenergic stress contributes to metabolic dysfunction and an exhausted phenotype in T cells in the tumor microenvironment

• Qiao G, Chen M, Mohammadpour H, MacDonald CR, Bucsek MJ, Hylander BL, Barbi JJ, Repasky EA

Epithelial Mutant p53 Promotes Resistance to Anti-PD-1-Mediated Oral Cancer Immunoprevention in Carcinogen-Induced Mouse Models

• Wang J, Hu Y, Escamilla-Rivera V, Gonzalez CL, Tang L, Wang B, El-Naggar AK, Myers JN, Caulin C

Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism

• Finlin BS, Memetimin H, Zhu B...Sullivan PG, Dupont-Versteegden EE, Kern PA

Il-10 signaling reduces survival in mouse models of synucleinopathy

• Cockey SG, McFarland KN, Koller EJ...Golde TE, Giasson BI, Chakrabarty P

Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells

• Louwe PA, Badiola Gomez L, Webster H, Perona-Wright G, Bain CC, Forbes SJ, Jenkins SJ