OLD Category: signatures

A phase Ib open-label dose escalation study of the safety, pharmacokinetics, and pharmacodynamics of cobimetinib (GDC-0973) and ipatasertib (GDC-0068) in patients with locally advanced or metastatic solid tumors

• Shapiro GI, LoRusso P, Cho DC...Sanabria-Bohorquez S, Meng RD, Bendell JC

Epigenetic Silencing of LMX1A Contributes to Cancer Progression in Lung Cancer Cells

• Wu TH, Chang SY, Shih YL, Chian CF, Chang H, Lin YW

Increased hepatic and circulating chemokine and osteopontin expression occurs early in human NAFLD development

• Kriss M, Golden-Mason L, Kaplan J, Mirshahi F, Setiawan VW, Sanyal AJ, Rosen HR

Personal Medicine and Bone Metastases: Biomarkers, Micro-RNAs and Bone Metastases

• Wood SL, Brown JE

Immune monitoring of interleukin-7 compassionate use in a critically ill COVID-19 patient

• Monneret G, de Marignan D, Coudereau R, Bernet C, Ader F, Frobert E, Gossez M, Viel S, Venet F, Wallet F

Human Respiratory Syncytial Virus-induced immune signature of infection revealed by transcriptome analysis of clinical pediatric nasopharyngeal swab samples

• Nicolas de Lamballerie C, Pizzorno A, Dubois J...Legras-Lachuer C, Terrier O, Rosa-Calatrava M

Small molecule AZD4635 inhibitor of A2AR signaling rescues immune cell function including CD103+ dendritic cells enhancing anti-tumor immunity

• Borodovsky A, Barbon CM, Wang Y...Fawell S, Schuller AG, Mele DA

Exosomal MicroRNAs in Pregnancy Provides Insight into a Possible Cure for Cancer

• Pillay P, Moodley K, Vatish M, Moodley J

Ribociclib, a CDK 4/6 inhibitor, plus endocrine therapy in Asian women with advanced breast cancer

• Yap Y, Chiu J, Ito Y...Han Y, Gazdoiu M, Masuda N

A refined cell-of-origin classifier with targeted NGS and artificial intelligence shows robust predictive value in DLBCL

• Xu-Monette ZY, Zhang H, Zhu F...Xu B, Albitar M, Young KH

Dysbiosis in intestinal microbiome linked to fecal blood determined by direct hybridization

• Cafiero C, Re A, Pisconti S...Fazio A, Caroleo MC, Cione E

Active Lysogeny in Listeria Monocytogenes Is a Bacteria-Phage Adaptive Response in the Mammalian Environment

• Pasechnek A, Rabinovich L, Stadnyuk O, Azulay G, Mioduser J, Argov T, Borovok I, Sigal N, Herskovits AA