OLD Category: signatures

Biomarkers associated with beneficial PD-1 checkpoint blockade in non-small-cell lung cancer (NSCLC) identified using high-plex digital spatial profiling

• Zugazagoitia J, Gupta S, Liu Y, Fuhrman K, Gettinger S, Herbst RS, Schalper KA, Rimm DL.

Digital quantitative assessment of PD-L1 using digital spatial profiling

• Gupta S, Zugazagoitia J, Martinez-Morilla S, Fuhrman K, Rimm DL

Prognostic Impact of Tumor-Associated Macrophages on Survival Is Checkpoint Dependent in Classical Hodgkin Lymphoma

• Karihtala K, Leivonen SK, Brück O, Karjalainen-Lindsberg ML, Mustjoki S, Pellinen T, Leppä S.

Clinical impact of combined epigenetic and molecular analysis of pediatric low-grade gliomas

• Fukuoka K, Mamatjan Y, Tatevossian R...Ellison D, Hawkins C, Tabori U

Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomized, open-label, phase 2 trial

• Goldberg SB, Schalper KA, Gettinger SN...Wei W, Chiang V, Kluger HM

Identification of microRNAs in bovine faeces and their potential as biomarkers of Johne’s Disease

• Shaughnessy RG et al.,

Comparison of GeneChip, nCounter and real-time polymerase chain reaction based gene expressions predicting loco-regional tumour control after primary and postoperative radiochemotherapy in head and neck squamous cell carcinoma

• Schmidt S et al.,

The potential of circulating exosomal RNA biomarkers in cancer

• Chu YL et al.,

Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes

• Clarke M, Mackay A, Ismer B...Jacques TS, Jones DT, Jones C

Microglial Depletion with CSF1R Inhibitor During Chronic Phase of Experimental Traumatic Brain Injury Reduces Neurodegeneration and Neurological Deficits

• Henry RJ, Ritzel RM, Barrett JP...Stoica BA, Faden AI, Loane DJ

Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases

• de Jesus AA, Hou Y, Brooks S...Wampler Muskardin T, Canna SW, Goldbach-Mansky R

The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models

• Tam BY et al.,