OLD Category: skin disease

Models that combine transcriptomic with spatial protein information exceed the predictive value for either single modality

• Vathiotis IA, Yang Z, Reeves J, Toki M, Aung TN, Wong P, Kluger H, Syrigos KN, Warren S, Rimm DL

Cutaneous Melanoma Classification: The Importance of High-Throughput Genomic Technologies

• Scatena C, Murtas D, Tomei S

Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy

• DeVito NC, Sturdivant M, Thievanthiran B...Novotny-Diermayr V, Strickler JH, Hanks BA

Transcriptomic analysis identifies differences in gene expression in actinic keratoses after treatment with imiquimod and between responders and non responders

• Trager MH, Rizk E, Rose S...Geskin LJ, Saenger YM, Goldenberg G

Multiplexed Immunohistochemistry and Digital Pathology as the Foundation for Next-Generation Pathology in Melanoma: Methodological Comparison and Future Clinical Applications

• Van Herck Y, Antoranz A, Andhari MD, Milli G, Bechter O, De Smet F, Bosisio FM

MYC oncogene is associated with suppression of tumor immunity and targeting Myc induces tumor cell immunogenicity for therapeutic whole cell vaccination

• Wu X, Nelson M, Basu M, Srinivasan P, Lazarski C, Zhang P, Zheng P, Sandler AD

Tilsotolimod with Ipilimumab Drives Tumor Responses in Anti–PD-1 Refractory Melanoma

• Haymaker C, Johnson DH, Murthy R...Markowitz J, Bernatchez C, Diab A

SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense

• Klopfenstein N, Brandt SL, Castellanos S, Gunzer M, Blackman A, Serezani CH

Distinct Signatures of Genomic Copy Number Variants Define Subgroups of Merkel Cell Carcinoma Tumors

• Hill NT, Kim D, Busam KJ, Chu EY, Green C, Brownell I

PSPH promotes melanoma growth and metastasis by metabolic deregulation-mediated transcriptional activation of NR4A1

• Rawat V, Malvi P, Della Manna D, Yang ES, Bugide S, Zhang X, Gupta R, Wajapeyee N

The glutaminase inhibitor CB-839 (Telaglenastat) enhances the anti-melanoma activity of T cell mediated immunotherapies

• Varghese S, Pramanik S, Williams LJ...Roszik J, Peng W, Vashisht Gopal YN

Ruxolitinib Cream Has Dual Efficacy on Pruritus and Inflammation in Experimental Dermatitis

• Scuron MD, Fay BL, Connell AJ, Peel MT, Smith PA