nCounter® Bulk Multiomics
RNA + Protein

Keep Me Updated on Bulk Multiomics

Multiomics Made Simple!
Same sample. Same platform. Same run.

The nCounter® platform is evolving. Now, you can measure RNA and protein together from the same FFPE or FF sample—in a three-step simple workflow, with results in just three days. Access the simplicity, precision, and speed of the nCounter Analysis System for both protein and RNA from the same FFPE sample. Bulk multiomics has never been easier.

Consistent Results from an Easy Bulk Multiomics Workflow

Bulk Multiomics Workflow

nCounter Bulk Multiomics Highlights

  • Sample to answer in 3 days: Rapidly generate actionable results with minimal hands-on-time, all from a single sample, same platform.
  • FFPE & FF compatible: Generate reliable answers from the most challenging sample types. Compatible with whole slide FFPE and Fresh Frozen (FF) samples.
  • Flexible Bulk Multiomics Panel Options: Customize your assay with stackable 200-300 plex protein panels combined with any nCounter Gene Expression Panel.
  • Integrated data analysis: Overcome bulk multiomic data harmonization challenges when using multiple platforms. Visualize RNA and proteins together or separately with pathways scoring, heat maps, volcano plots and correlation maps.

Flexible Bulk Multiomics Panel Options

Stackable 200-300 plex proteins panels can be combined with any nCounter Gene Expression Panel.

Coming soon:

Immune Pathways nCounter Protein Panel

Tumor Signaling nCounter Protein Panel

Stay updated with the latest nCounter bulk multiomics information as it releases! Updates will be rapid and plentiful over the coming months- get on our mailing list today so you don’t miss anything!

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nCounter Multiomics TAP flyer

nCounter Multiomics FAQs

What are the advantages of nCounter multiomics over other multiomic solutions?

The nCounter multiomics solution offers several key advantages over other potential solutions, including workflow simplicity, sample flexibility, speed to results and data integration.

  • Only platform to provide multiomic answers from the same sample in the same run.

  • Automated workflow with a short turn-around time: sample to answer in 3 days

  • Compatible with challenging sample types, like FFPE

  • Large selection of RNA panels to run with the protein panels

  • Flexible multiomics panel options- custom targets can be added to predesigned panels

  • End-to-end solution with integrated data analysis
What sample types are supported for multiomics on nCounter?

Initial offerings are compatible with FFPE and FF tissue. Additional protocols for lysates will be available soon. The initial multiomics protocol will focus on whole slide FFPE tissues as well as fresh frozen tissue. Additional protocols are being developed for cell lysate and plasma sample types and will launch in 2026.

What will the data analysis solution look like for multiomics?

We will be introducing a new analysis software with multiomics analysis capabilities. One of the primary benefits of multiomics on nCounter is that the data for both analytes (RNA + Protein) is all the same direct digital counts. This makes it possible to combine data visualizations including heat maps, volcano plots as well as correlation tables that compare gene expression and protein expression. Additionally, already existing gene expression-only data can be combined with protein data from multiomics studies using the updated pipeline.

What protein content will be available at launch?

The initial protein panels at launch will include human panels focused on immune pathways and tumor signaling. The content for these panels was designed to complement our nCounter Oncology or Immunology panels, including our popular 360 series. Custom capabilities for proteins will also launch as an antibody labeling kit capable of labeling 5-10 antibodies. After the initial launch, Bruker will explore the development of additional panels. If there is a focus area you would like to see- please let us know! We’d love to hear from you. 

How are the antibodies in the protein panels validated?

nCounter protein panels include antibodies that have been validated at various stages of development and manufacturing. Antibodies acquired through a partnership with Abcam arrive with validation data that includes up to 10 different methods (Western blot, ICC, IHC, ELISA, IP, ChIP, flow cytometry, peptide array and dot blot). All antibodies included in the nCounter panels also have Abcam IHC associated images. Additionally, as part of development and manufacturing, BSB performs a series of validation testing. A comprehensive white paper outlining the commercial protein panel validation will be available later this year- stay tuned for more details!