Spatial Tissue Book

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See Also:
GeoMx DSP Technology Access Program
CosMx SMI Technology Access Program

What is the Spatial Tissue Book?

The Spatial Tissue Book is a repository of images, data, selection and segmentation strategies for different tissue types and diseases that have been analyzed through either the GeoMx® DSP Technology Access Program or the CosMx™ SMI Technology Access Program.

Each individual PDF page of the Tissue Book includes images of the tissue and is annotated by the disease(s) studied, species of interest, and type of assay performed.

Why Use the Tissue Book?

  • See representative images for tissues and/or disease areas that you are studying.
  • Get ideas on how to select ROIs and segment the tissue to meet your study design needs.
  • Review spatial transcriptomics data from different tissues representing various diseases.
Explore the anatomy of a GeoMx tissue book page
Tissue Book page example with charts, images, diagrams and other information

  • The type of tissue and disease profiled.

  • Learn about the application and study design.

  • Get a high-level overview of what kind of sample type was used, species, strategy for area of illumination as well as the assay and morphology markers used. Learn how many targets were detected from the assay for this particular study.

  • See an actual image taken with either the GeoMx Digital Spatial Profiler or the CosMx Spatial Molecular Imager annotated with the different fluorescent markers used to outline tissue morphology and/or cell types.

  • Learn more about the Segmentation Strategy and how individual regions of interest were compartmentalized into different areas of illumination and/or cell type populations.

  • See how many targets were detected above the background for each tissue compartment and/or cell type profiled.

  • View additional plots showing the results of the study.

  • Here you can click on this link to visit our Morphology Marker page to learn about which fluorescently-tagged antibodies or RNAScope Probes have been used on the GeoMx DSP.

Tissue Book Collection

Browse entries here, or just download the complete tissue book.

Filter Entries

          Tissue Tissue Biology Species Type Assay Instrument
          Lung NSCLC HumanFFPE1000-Plex Human RNA Universal Cell CharacterizationCosMxDownload
          Liver Normal HumanFFPE1000-Plex Human RNA Universal Cell CharacterizationCosMxDownload
          Liver Hepatocellular Carcinoma HumanFFPE1000-Plex Human RNA Universal Cell CharacterizationCosMxDownload
          Brain Normal MouseFresh FrozenCosMx Mouse Neuroscience PanelCosMxDownload
          Breast Breast Cancer HumanFFPE1000-Plex Human RNA Universal Cell CharacterizationCosMxDownload
          KidneyPediatric Renal AllograftHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          Lymph NodeLymphomaHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          LungLung CancerHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          SkinHidradenitis SuppurativaHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          BrainParkinson's DiseaseMouseFFPEMouse Whole Transcriptome AtlasGeoMxDownload
          OvaryOvarian CancerHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          Brain Schizophrenia HumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          BreastBreast CancerHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          ColonColonic AdenomaHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          EsophagusBarrett's MucosaHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          KidneyKidney CancerHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          LiverHepatocellular CarcinomaHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          LungCOVID-19HumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          LungTuberculosisHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          LungNSCLCHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          MuscleMyositisHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          PlacentaChronic Intervillositis of Unknown EtiologyHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          ProstateProstate CancerHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload
          SkinMelanomaHumanFFPEHuman Whole Transcriptome AtlasGeoMxDownload

          Related Resources

          DSP Technology Access Program
          CosMx SMI Technology Access Program
          GeoMx Morphology Markers
          Spatial Organ Atlas