OLD Category: immunology

LAG3: a novel immune checkpoint expressed by multiple lymphocyte subsets in diffuse large B-cell lymphoma

• Keane C, Law SC, Gould C, Birch S, Sabdia MB, Merida de Long L, Thillaiyampalam G, Abro E, Tobin JW, Tan X, Xu-Monette ZY, Young KH, Gifford G, Gabreilli S, Stevenson WS, Gill A, Talaulikar D, Jain S, Hernandez A, Halliday SJ, Bird R, Cross D, Hertzberg M, Gandhi MK

Biomarkers associated with beneficial PD-1 checkpoint blockade in non-small-cell lung cancer (NSCLC) identified using high-plex digital spatial profiling

• Zugazagoitia J, Gupta S, Liu Y, Fuhrman K, Gettinger S, Herbst RS, Schalper KA, Rimm DL.

Digital quantitative assessment of PD-L1 using digital spatial profiling

• Gupta S, Zugazagoitia J, Martinez-Morilla S, Fuhrman K, Rimm DL

Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies

• Kim H et al.,

Prognostic Impact of Tumor-Associated Macrophages on Survival Is Checkpoint Dependent in Classical Hodgkin Lymphoma

• Karihtala K, Leivonen SK, Brück O, Karjalainen-Lindsberg ML, Mustjoki S, Pellinen T, Leppä S.

Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomized, open-label, phase 2 trial

• Goldberg SB, Schalper KA, Gettinger SN...Wei W, Chiang V, Kluger HM

Identification of microRNAs in bovine faeces and their potential as biomarkers of Johne’s Disease

• Shaughnessy RG et al.,

Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases

• de Jesus AA, Hou Y, Brooks S...Wampler Muskardin T, Canna SW, Goldbach-Mansky R

Striatin heterozygous mice are more sensitive to aldosterone-induced injury

• Garza AE, Trefts E, Katayama Rangel IA, Brooks D, Baudrand R, Moize B, Romero JR, Ranjit S, Treesaranuwattana T, Yao TM, Adler GK, Pojoga LH, Williams GH.

A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells

• Bose S, Volpatti LR, Thiono D...Greiner DL, Langer R, Anderson DG

High-fat diet-induced GAIT element-mediated translational silencing of mRNAs encoding inflammatory proteins in macrophage protects against atherosclerosis

• Basu A et al.,

Arx expansion mutation perturbs cortical development by augmenting apoptosis without activating innate immunity in a mouse model of X-linked infantile spasms syndrome

• Siehr MS et al.,