
Category: immunology
June 8, 2023 / J Inflamm Res
The Technical Feasibility of Digital Spatial Profiling in Immune/Inflammation Study of Thrombosis
Background: A comprehensive study of the distribution and role of immune/inflammatory cells in thrombosis is still lacking because traditional pathology techniques cannot accomplish the analysis of numerous protein and genetic…
June 6, 2023 / J Hepatol
Morphologic and molecular analysis of liver injury after SARS-CoV-2 vaccination reveals distinct characteristics
Background and Aims: Liver injury after COVID-19 vaccination is very rare and shows clinical and histomorphological similarities with autoimmune hepatitis (AIH). Little is known about the pathophysiology of COVID-19 vaccine-induced…
May 29, 2023 / Nat Med
Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
Tumor-infiltrating T cells offer a promising avenue for cancer treatment, yet their states remain to be fully characterized. Here we present a single-cell atlas of T cells from 308,048 transcriptomes…
April 5, 2023 / Eur Heart J Cardiovasc Pharmacother
Vascular mechanisms of post-COVID-19 conditions: Rho-kinase is a novel target for therapy
Background: In post-coronavirus disease-19 (post-COVID-19) conditions (long COVID), systemic vascular dysfunction is implicated, but the mechanisms are uncertain, and the treatment is imprecise. Methods and results: Patients convalescing after hospitalization…
March 10, 2023 / Toxins
Mapping the Immune Cell Microenvironment with Spatial Profiling in Muscle Tissue Injected with the Venom of Daboia russelii
Pathological and inflammatory events in muscle after the injection of snake venoms vary in different regions of the affected tissue and at different time intervals. In order to study such…
December 13, 2022 / Neurobiol Aging
Signatures for Viral Infection and Inflammation in the Proximal Olfactory System in Familial Alzheimer’s Disease
November 21, 2022 / JHEP Reports
Spatial molecular and cellular determinants of STAT3 activation in liver fibrosis progression in non-alcoholic fatty liver disease
November 11, 2022 / Sci Immunol
Local IL-23 is required for proliferation and retention of skin-resident memory TH17 cells
October 27, 2022 / Mucosal Immunol