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nCounter® miRNA Expression Panels

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Helping Your Research

Conventional technologies for small RNA profiling like RNAseq can be costly, onerous, and require complex data analysis. In addition, they require RNA purification and multiple enzymatic steps that can be challenging for biofluid samples like serum and plasma. When developing reliable and robust miRNA signatures for different diseases, you need a robust and reliable platform that works well with multiple sample types. 

nCounter miRNA Expression Panels utilize NanoString’s amplification-free technology to do expression profiling by direct quantification of individual RNA molecules. The assay detects miRNAs without the use of reverse transcription or amplification by using molecular barcodes. Therefore, it is easier and faster to validate miRNA biomarkers as compared to RNASeq or PCR-based platforms and the results are highly reproducible. With nCounter miRNA Expression Panels, you can:

  • Reliably detect and quantitate the most biologically relevant human, mouse, or rat miRNAs directly from FFPE, blood, or biofluids
  • Skip laborious library prep and process your samples with less than one hour of hands-on time 
  • Experience unparalleled reproducibility and specificity with a dynamic range of six logs
  • Receive publication-ready figures within 24 hours with robust, off-the-shelf data analysis solutions
miRNA illustration

How It Works

nCounter miRNA Expression panels are designed to provide a sensitive, reproducible, and highly multiplexed method for detecting miRNAs in total RNA across all biological levels of expression. The assay can be run on total RNA isolated from any source, including formalin-fixed paraffin embedded (FFPE) tissue sections

01:

Off-the-shelf assays are available for probing hundreds of miRNAs from human, mouse, and rat

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Create a custom a la carte miRNA assay

Pick 20-50 miRNAs of your choice from the list of miRNAs included in the human, mouse, and rat miRNA panels

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Custom design options

Panel Selection Tool

Find the gene expression panel for your research with easy to use panel pro

Find Your Panel

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Product Specifications
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Related Resources

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Product Bulletin miRNA – Product Bulletin
Whitepaper Human miRNA – Whitepaper
App Note/Tech Note Tech Note – miRNA Analysis in Plasma and Serum
Blog miRNA Profiling in Malignant Melanoma: Making “Australia’s National Cancer” Obsolete.
Blog Q&A with Dr. Juliane Nguyen: Exosome Profiling with miRNA and Biotech’s Next Breakthrough

Publications

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Idelalisib inhibits experimental proliferative vitroretinopathy.

Proliferative vitreoretinopathy (PVR) is a fibrotic eye disease that develops after rhegmatogenous retinal detachment surgery and open-globe traumatic injury. Idelalisib is a specific inhibitor of phosphoinositide 3-kinase (PI3K) δ.

Comparative spatial transcriptomic and single-cell analyses of human nail units and hair follicles demonstrate transcriptional similarities between the onychodermis and follicular dermal papilla.

The nail unit and hair follicle are both hard keratin-producing organs that share various biological features. Here we used a Digital Spatial Profiling (DSP) and single cell RNA sequencing (scRNA-seq) to define a spatially resolved expression profile of the human nail unit and hair follicle.

Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.

Rationale: The incidence and sites of mucus accumulation, and molecular regulation of mucin gene expression, in COVID-19 lung disease have not been reported. Objectives: Characterize incidence of mucus accumulation and the mechanisms mediating mucin hypersecretion in COVID-19 lung disease.

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