nCounter® miRNA Expression Panels

Helping Your Research

Conventional technologies for small RNA profiling like RNAseq can be costly, onerous, and require complex data analysis. In addition, they require RNA purification and multiple enzymatic steps that can be challenging for biofluid samples like serum and plasma. When developing reliable and robust miRNA signatures for different diseases, you need a robust and reliable platform that works well with multiple sample types. 

nCounter miRNA Expression Panels utilize NanoString’s amplification-free technology to do expression profiling by direct quantification of individual RNA molecules. The assay detects miRNAs without the use of reverse transcription or amplification by using molecular barcodes. Therefore, it is easier and faster to validate miRNA biomarkers as compared to RNASeq or PCR-based platforms and the results are highly reproducible. With nCounter miRNA Expression Panels, you can:

  • Reliably detect and quantitate the most biologically relevant human or mouse miRNAs directly from FFPE, blood, or biofluids
  • Skip laborious library prep and process your samples with less than one hour of hands-on time 
  • Experience unparalleled reproducibility and specificity with a dynamic range of six logs
  • Receive publication-ready figures within 24 hours with robust, off-the-shelf data analysis solutions
miRNA illustration

How It Works

nCounter miRNA Expression panels are designed to provide a sensitive, reproducible, and highly multiplexed method for detecting miRNAs in total RNA across all biological levels of expression. The assay can be run on total RNA isolated from any source, including formalin-fixed paraffin embedded (FFPE) tissue sections

01:

Off-the-shelf assays are available for probing hundreds of human and mouse miRNAs

02:

Create a custom a la carte miRNA assay

Pick 20-50 miRNAs of your choice from the list of miRNAs included in the human and mouse miRNA panels

03:

Custom design options

Panel Selection Tool

Find the gene expression panel for your research with easy to use panel pro

Find Your Panel

Product Information

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Product Specifications
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Related Resources

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Product Bulletin miRNA – Product Bulletin
Whitepaper Human miRNA – Whitepaper
App Note/Tech Note Tech Note – miRNA Analysis in Plasma and Serum
Blog Post miRNA Profiling in Malignant Melanoma: Making “Australia’s National Cancer” Obsolete.

Publications

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Multiomic spatial landscape of innate immune cells at human central nervous system borders

The innate immune compartment of the human central nervous system (CNS) is highly diverse and includes several immune-cell populations such as macrophages that are frequent in the brain parenchyma (microglia) and less numerous at the brain interfaces as CNS-associated macrophages (CAMs). Due to their scantiness and particular location, little is known about the presence of temporally and spatially restricted CAM subclasses during development, health and perturbation.

BCG vaccination stimulates integrated organ immunity by feedback of the adaptive immune response to imprint prolonged innate antiviral resistance

Biologically derived epicardial patch induces macrophage mediated pathophysiologic repair in chronically infarcted swine hearts

There are nearly 65 million people with chronic heart failure (CHF) globally, with no treatment directed at the pathologic cause of the disease, the loss of functioning cardiomyocytes. We have an allogeneic cardiac patch comprised of cardiomyocytes and human fibroblasts on a bioresorbable matrix.

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