Category: pathogens

Viperin is anti-viral in vitro but is dispensable for restricting dengue virus replication or induction of innate and inflammatory responses in vivo.

• Al Shujairi WH, Kris LP, van der Hoek K, Cowell E, Bracho-Granado G, Woodgate T, Beard MR, Carr JM

Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacterium tuberculosis Infection.

• Duffy D, Nemes E, Llibre A...Bilek N, Scriba TJ, Albert ML

Essential role of M1 macrophages in blocking cytokine storm and pathology associated with murine HSV-1 infection.

• Jaggi U, Matundan HH, Yu J, Hirose S, Mueller M, Wormley FL, Ghiasi H

A Transcriptomic Severity Metric That Predicts Clinical Outcomes in Critically Ill Surgical Sepsis Patients.

• Brakenridge SC, Starostik P, Ghita G...Liesenfeld O, Sweeney TE, Moldawer LL

Podoplanin Drives Motility of Active Macrophage via Regulating Filamin C During Helicobacter pylori Infection.

• Cheok YY, Tan GMY, Fernandez KC, Chan YT, Lee CYQ, Cheong HC, Looi CY, Vadivelu J, Abdullah S, Wong WF

The Short-Chain Fatty Acids Propionate and Butyrate Augment Adherent-Invasive Escherichia coli Virulence but Repress Inflammation in a Human Intestinal Enteroid Model of Infection.

• Pace F, Rudolph SE, Chen Y, Bao B, Kaplan DL, Watnick PI

Host response transcriptomic analysis of Crimean-Congo hemorrhagic fever pathogenesis in the cynomolgus macaque model.

• Arnold CE, Shoemaker CJ, Smith DR, Douglas CE, Blancett CD, Graham AS, Minogue TD

Type I interferon response and vascular alteration in chilblain‐like lesions during the COVID‐19 outbreak.

• Frumholtz L, Bouaziz J, Battistella M...Gendron N, Smadja D, Cassius C

Early nasal type I IFN immunity against SARS-CoV-2 is compromised in patients with autoantibodies against type I IFNs.

• Lopez J, Mommert M, Mouton W, Pizzorno A, Brengel-Pesce K, Mezidi M, Villard M, Lina B, Richard JC, Fassier JB, Cheynet V, Padey B, Duliere V, Julien T, Paul S, Bastard P, Belot A, Bal A, Casanova JL, Rosa-Calatrava M, Morfin F, Walzer T, Trouillet-Assant S

Host-Pathogen Interactions of Chlamydia trachomatis in Porcine Oviduct Epithelial Cells.

• Amaral AF, McQueen BE, Bellingham-Johnstun K, Poston TB, Darville T, Nagarajan UM, Laplante C, Kaser T

Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures.

• Kulasinghe A, Chin Wee Tan, Anna Flavia Ribeiro dos Santos Miggiolaro, James Monkman, Habib SadeghiRad, Dharmesh D. Bhuva, Jarbas da Silva Motta Junior, Caroline Busatta Vaz de Paula, Seigo Nagashima, Cristina Pellegrino Baena, Paulo Souza-Fonseca-Guimaraes, Lucia de Noronha, Timothy McCulloch, Gustavo Rodrigues Rossi, Caroline Cooper, Benjamin Tang, Kirsty R. Short, Melissa J. Davis, Fernando Souza-Fonseca-Guimaraes, Gabrielle T. Belz, Ken O'Byrne

Limited TCR repertoire and ENTPD1 dysregulation mark late-stage COVID-19.

• Wang N, Vuerich M, Kalbasi A...Shaefi S, Robson SC, Longhi MS