Resource Type: Blog

The CosMx® Spatial Molecular Imager (SMI) instrument performs fluorescent imaging to read out in-situ hybridized fluorescent reporters which uniquely identify RNA transcripts. The presence of tissue autofluorescence background may reduce…

Single-cell RNA sequencing (scRNA-seq) has transformed molecular biology by enabling high-throughput transcriptional profiling at cellular resolution. But as powerful as scRNA-seq is, it comes with trade-offs: loss of spatial information,…

Discover the future of spatial biology! Read about our AGBT 2025 eBook featuring posters highlighting powerful new breakthroughs EpicIF, CosMx WTX, and InSituDiff, plus on-demand workshop access.

Learn how CosMx WTX brings whole-transcriptome coverage to every cell in FFPE tissues, uncovering truly groundbreaking spatial biology.

Discover Dr. Miranda Orr’s cutting-edge spatial multiomics research in neuroscience, revealing new Alzheimer’s disease processes with advanced proteomic tools.

Single-cell spatial biology opens doors to unprecedented scientific questions requiring the development of new computational workflows and approaches to analyze and interpret data. Whether you are new to single-cell spatial…

We are excited to share the third installment of tips for successful CosMx™ SMI single-cell spatial runs at 1000-plex. Our first installment of tips focused on data by tissue and…

We are excited to share the second installment of tips for successful CosMx™ SMI single-cell spatial runs at 1000-plex. Our first installment of tips focused on data by tissue and…

For researchers studying diseases that cruelly take the lives of millions — Alzheimer’s disease, lung, colon, breast, and pancreatic cancer, among others — it has been a long-held dream to…

We are excited to share insights and recommendations to enhance your experience with CosMx™ SMI 1000-plex RNA assays. The quality of single-cell spatial data is influenced by various factors, and…

The GeoMx Digital Spatial Profiler (DSP) is a powerful tool for spatial multiomics, the in situ analysis of RNA and protein expression in tissue sections. GeoMx DSP gives you the…

Gene expression profiling (GEP) signatures, comprising sets of genes characteristic of specific diseases, tissues, cell types, cell states, or biological perturbation, hold significant diagnostic, predictive, and prognostic value, positioning them…