Resource Type: Blog

Gene expression profiling (GEP) signatures, comprising sets of genes characteristic of specific diseases, tissues, cell types, cell states, or biological perturbation, hold significant diagnostic, predictive, and prognostic value, positioning them…

In research, scientists are continually pushing boundaries to gain deeper insights into biology, medicine, and drug discovery. Single-cell spatial imaging has emerged as a powerful technology in the field of…

Introduction to the TIS Gene Expression Profile Innovations in multiplex gene expression analysis are revolutionizing translational research and clinical practices by enabling identification of gene signatures involved in various biological…

NanoString and Illumina have collaborated to release two new demo datasets of GeoMx Digital Spatial Profiler (DSP) data on the Illumina BaseSpace Sequence Hub (BSSH) cloud.  Spatial proteogenomics enables new…

The Need for Gene Expression Profiling Gene expression profiling has emerged as a genomic tool that can help decipher the complexity of cancer subtyping. Conceptually, cancer is a fairly simple…

The Human Protein Atlas is one of the world’s largest biological databases, containing spatial expression profiles for all known proteins expressed in human organs and tissues. It contains a vast…

Tissue and cell samples constitute the main source of samples for protein or RNA expression analysis in biology and help us understand how cells interact, organize themselves, and drive various…

The transcriptome is the sum of all the RNA in an organism’s cells and tissues being actively transcribed at any given time from genomic DNA. It includes protein-coding messenger RNA (mRNA)…

Immunofluorescence staining was first used in 1942 and has since remained a highly reliable and powerful technique for a wide range of research and diagnostics. The principle of immunofluorescence is…

The goal of the Human Protein Atlas (HPA) project is to map all human proteins in cells, tissues, and organs.  Further, it aims to annotate the function and spatial distribution of…

Understanding tissue morphology is crucial to identify and separate regions of tissue into meaningful biological groupings for image analysis of tissue sections. This is done using morphological markers, most of…

Immunofluorescence techniques are being increasingly used as an imaging and diagnostic tool in clinical pathology, oncology, and infectious disease, particularly for the study of biomarkers related to cancer diagnosis, prognosis,…