Ragon Institute Spatial Day

In-Person Seminar, Virtual Seminar
Ragon Institute of MGH, MIT and Harvard, Schwarz Auditorium, 400 Technology Square, Cambridge, MA 02139-3583Link

The CosMx™ Spatial Molecular Imager – A High-plex, Single-cell Spatial Biology Platform Capable of Visualizing up to 6,000 Transcripts in Multiple Tissue Types

At this seminar, we will highlight NanoString Technologies’ newest spatial biology platform, the CosMx Spatial Molecular Imager (SMI) . The CosMx SMI is the most comprehensive, fully integrated in situ spatial solution to provide spatial multiomics with formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue samples at cellular and subcellular resolution. The CosMx SMI currently enables rapid quantification and visualization of up to 1,000 RNA and 64 protein validated analytes—with the CosMx Human 6k Discovery Panel launching soon.


12:45 p.m. – Lunch is served

1:00-2:30 p.m. – Presentations

2:30-3:00 p.m. – Question and answer session


Circular portrait of Joe Beechem

Joseph Beechem, PhD, Chief Scientific Officer and Senior Vice President of Research and Development, NanoString Technologies
Spatial-omics Revolution: Innovation Roadmap and Key Applications

Sizun Jiang, PhD, Assistant Professor, Harvard Medical School; Principal Investigator, Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center
Spatial-omics to Interrogate Host-disease Interactions

Thomas Diefenbach, PhD, Assistant Director, Ragon Institute Imaging Core, Ragon Institute of MGH, MIT, and Harvard
Host of the question and answer session

Expertise on site

Amy Wahba, PhD, Senior Technical Sales Specialist, NanoString Technologies

Erroll Rueckert, PhD, Senior District Sales Manager, NanoString Technologies

Carolyn Kirby Merigan, Regional Account Manager, NanoString Technologies


Joseph Beechem, PhD

Chief Scientific Officer and Senior Vice President of Research and Development, NanoString

Joseph M. Beechem, PhD, has served as the chief scientific officer and senior vice president of Research and Development at NanoString Technologies since April 2012. He has authored more than 200 peer-reviewed papers, averaging more than four citations each day, in diverse fields such as cancer immunology, infectious disease, imaging, biomathematics, physics, chemistry, spectroscopy, and diagnostics. In addition, Joseph Beechem is named on nearly 50 US patents or patent applications and has served on several editorial and scientific advisory boards. Joseph Beechem received a BS in Chemistry and Biology from Northern Kentucky University and a PhD in Biophysics from Johns Hopkins University.

Sizun Jiang, PhD

Assistant Professor; Principal Investigator, Harvard Medical School; Beth Israel Deaconess Medical Center

Sizun Jiang, PhD, completed his PhD training at Harvard University where he made significant strides in the field of host-pathogen chromatin interactions during viral-driven lymphomagenesis under the guidance of Professor Elliott Kieff. His pursuit of knowledge then led him to Stanford University where he worked with Professor Garry Nolan to develop and apply groundbreaking spatial technologies to better understand biological systems. Currently, as an assistant professor at Harvard Medical School and Beth Israel Deaconess Medical Center, Sizun's research stands at the forefront of innovation, focusing on the intersection of host-disease interactions through the development and application of novel spatial technology platforms and computational algorithms. His ongoing work delves into the intricacies of viral pathogenesis, tumor biology, and immune dysregulation.

Thomas Diefenbach, PhD

Associate Director, Ragon Institute Imaging Core, Ragon Institute of MGH, MIT, and Harvard

Thomas Diefenbach, PhD, received his PhD in neurobiology in Edmonton, Canada, and performed his postdoctoral research at the University of Utah Medical School in Salt Lake City and at the Department of Physiology at Tufts University in Boston. He managed an imaging facility at Boston Children’s Hospital, was an instructor of neurology and pediatrics with Harvard Medical School, and managed a two-photon imaging facility and worked in the Research Laboratory of Electronics at MIT. Thomas is currently associate director of the Ragon Institute Imaging Core at the Ragon Institute for MGH, MIT and Harvard.