Spatial Day at the Lunenfeld-Tanenbaum Research Institute

In-Person Seminar, Virtual Seminar
Mount Sinai Hospital, Room L3-201, 60 Murray St, Toronto, ON M5T 3L9, CanadaLink

Profile the entire transcriptome and more than 570 proteins on a single slide

NanoString Technologies is thrilled to collaborate with our following partners on this event

Illumina logo

This event is ONLY accepting virtual registration at this time.

Exciting news! The GeoMx Digital Spatial Profiler (DSP) can profile over 570 proteins and the entire transcriptome on a single formalin-fixed, paraffin-embedded or fresh-frozen tissue sample. The GeoMx DSP is available to researchers at the Lunenfeld-Tanenbaum Research Institute (LTRI) through the Network Biology Collaborative Centre (NBCC) located at the LTRI in Mount Sinai Hospital.

In addition, we will introduce you to the CosMx Spatial Molecular Imager (SMI). The CosMx SMI is the most comprehensive, fully integrated in situ spatial solution to provide spatial multiomics with formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue samples at cellular and subcellular resolution. The CosMx SMI currently enables rapid quantification and visualization of up to 1,000 RNA and 64 protein validated analytes—with the CosMx Human 6k Discovery Panel launching soon.

Join us at this spatial day in partnership with Illumina to learn more about this innovative technology that allows for spatial profiling of RNA and protein targets on a single slide. With its advanced capabilities, the GeoMx DSP is revolutionizing research in fields such as cancer, immunology, and neuroscience.

Agenda

12:00 to 12:30 p.m. – Lunch is provided

  • 12:30 to 12:45 p.m. — Welcome and introduction
    • Jeff Wrana, PhD, Senior Investigator at the LTRI in the Mount Sinai Hospital
    • Natalie Shier, Executive Territory Account Manager at Illumina
    • Amir Farooqui, Regional Account Manager at NanoString Technologies
  • 12:45 to 1:35 p.m. — Profile 18,000 RNA transcripts and 570 proteins on a single slide with the GeoMx Digital Spatial Profiler and an introduction to the CosMx Spatial Molecular Imager
    • Seth Meyers, Manager of Technical Sales at NanoString Technologies
  • 1:35 to 2:05 p.m. — Illumina Solutions for Spatial Multiomics
    • Lisa Lock, PhD, Senior Genomics Specialist at Illumina
  • 2:05 to 2:35 p.m. — A GeoMx DSP research project completed at the LTRIUsing spatial transcriptomics to delineate markers of pre-malignant and malignant oral cancer
    • Ricky Tsai, Research Scientist in the Schramek lab at the LTRI in the Mount Sinai Hospital
  • 2:35 to 2:50 p.m. — Getting a GeoMx Digital Spatial Profiler project completed at the LTRI and announcement of a GeoMx DSP project grant
    • Amir Farooqui, Regional Account Manager at NanoString Technologies
  • 2:50 to 3:00 p.m. — Ask the experts wrap-up

Speakers

Jeff Wrana, PhD

Senior Investigator, Senior Investigator, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital; Professor, University of Toronto; Director, Network Biology Collaborative Centre

Jeff Wrana, PhD, is a Senior Investigator at Mount Sinai Health’s Lunenfeld-Tanenbaum Research Institute (LTRI), a Professor in the Department of Molecular Genetics at the University of Toronto, and the Mary Janigan Research Chair in Molecular Cancer Therapeutics. His research aims to understand how diverse signaling pathways interact to regulate cell behavior in development, tissue regeneration, and cancer. Jeff is the Director of the Network Biology Collaborative Centre that incorporates high-throughput screening strategies with next-generation sequencing and proteomics. He is an expert in single-cell biology, which his team used to discover a novel, injury-induced stem cell of the intestinal epithelium. He was inducted into the Royal Society of Canada in 2006 and received numerous awards for his work including the Premier’s Summit Award, a Queen Elizabeth II Diamond Jubilee Medal, and the McLaughlin Medal from the Royal Society of Canada.

Ricky Tsai

Research Scientist in the Schramek lab, Lunenfeld-Tanenbaum Research Institute in the Mount Sinai Hospital

Ricky Tsai is a research scientist in the lab of Daniel Schramek, PhD. His lab uses ultrasound-guided, in utereo injections of lentiviral RNAi and CRISPR libraries to elucidate genes responsible for tumor formations and to screen for potential cancer therapeutic targets. Ricky has used the GeoMx Digital Spatial Profiler while working with hospital pathologists to gain some insights on the gene markers that are found in pre-malignant and malignant oral cancer.

Seth Meyers

Manager, Technical Sales, NanoString Technologies

Seth Meyers has twenty years of experience in life science ranging from product development, marketing, sales and support. For the past ten years, Seth has supported NanoString Technologies first with the launch of the GeoMx Digital Spatial Profiler and more recently with the CosMx Spatial Molecular Imager.

Lisa Lock, PhD

Senior Genomics Specialist, Illumina

Lisa Lock, PhD, has been with Illumina for twelve years as a staff field application scientist and currently as a senior genomics specialist. She obtained her PhD in Biochemistry at McGill University, Montreal, studying molecular oncology, specifically receptor tyrosine kinase signaling in normal versus tumor cells. Prior to Illumina, she did a postdoc at the University of Toronto in cell signaling and worked as a research scientist at Lorus Therapeutics in Toronto developing anti-cancer and anti-microbial therapeutics.

Amir Farooqui

Regional Account Manager, NanoString Technologies

Amir Farooqui is a Regional Account Manager for NanoString Technologies. He has a background in science and technology and over 14 years of life science commercial operations experience with both academia and industry. Amir focuses on customer experience and brings a consultative value to identifying the right type of technologies for scientists to further their research.

Natalie Shier

Territory Account Manager, Illumina

Natalie Shier is a Territory Account Manager at Illumina. She has been in the industry for over 20 years, supporting customers with their genetic sciences and molecular biology needs while working for several companies including Thermo Fisher Scientific, Applied Biosystems, Invitrogen, and Qiagen. Natalie obtained her Honors Bachelor of Science in Life Sciences from Queen’s University.