Astrocytes & Microglia & Oligodendrocytes, Oh My! Glial Profiling with Multiplexed, Direct Digital Gene Expression and Benchside Chat with 3 Neuroscientists
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Comprehensively study the role of astrocytes, microglia, and oligodendrocytes in health and disease with the nCounter Glial Profiling Panel. Decipher the complex interplay between glial cells, peripheral immune cells, and neurons that underlies neurodegenerative & neuroinflammatory disorders and neurotrauma such as stroke, spinal cord injury, and traumatic brain injury.
Join Senior Field Applications Scientist Allison Songstad, PhD, to review case studies and how this panel was developed. Built to profile 770 human or mouse genes across 50+ pathways involved in glial cell biology and quantify the relative abundance of 5 CNS cell types and 14 peripheral immune cells.
Following this introduction, we’ll have a “benchside chat” with three scientists studing various aspects of neuroscience research. Tanseem Sharma, PhD, assistant professor at Indiana University; Kristan Worthington, PhD, assistant professor at University of Iowa; and Gabriela Goldberg, Biomedical Sciences PhD Student in the laboratory of Alysson Muotri at the University of California – San Diego.
Research interests of our guests:
Tasneem Sharma, PhD – translational science; disease modeling glaucoma with stem cell models and pressure chambers
Kristan Worthington, PhD – tissue engineering; using stem cells and 3D printing to engineer retinas for cell replacement therapies.
Gabriela Goldberg, BS – translational science; disease modeling a neuro-developmental disorder with stem cell-derived neurons and glia.
Allison Songstad, PhD
Senior Field Applications Scientist, NanoString Technologies
Allison Songstad received her PhD at the University of Iowa in Budd Tucker’s lab where she researched how induced pluripotent stem cells can be used to develop treatments for macular degeneration. After she graduated she worked in Larry Goldstein’s stem cell lab at the University of California – San Diego as a postdoctoral fellow studying how glial cells play a role in autism spectrum disorders. She currently supports researchers in the Eastern US as a Senior Field Applications Scientist with NanoString.
Tasneem Sharma, PhD
Assistant Professor, Indiana University
Dr. Tasneem Sharma is an Assistant Professor at Indiana University School of Medicine in the Department of Ophthalmology. Her passion lies in the scientific exploration of pathogenictranslaminar pressure induced neurodegeneration, neuronal cell death and generation of pluripotent stem cells (iPSCs) for disease modeling. She utilizes human stem cells to develop retinal neurons and has patented the translaminar autonomous system for studying various diseases affected by translaminar pressure differences. She aims to identify therapeutic interventions geared towards retinal ganglion cell survival through viral gene therapies, CRIPSR-Cas9 genome editing tools, cell and molecular biology techniques, bioengineering paradigms and neurotrophic factors. Her research efforts are committed to driving interventions that can improve public health care.
Kristan Worthington, PhD
Assistant Professor, University of Iowa
Dr. Worthington, Assistant Professor at the University of Iowa and a Researcher at the Wynn Institute for Vision Research. Her laboratory specializes intissue engineering; using stem cells and 3D printing to engineer retinas for cell replacement therapies.
Gabriela Goldberg, BS
Biomedical Sciences PhD Student, University of California - San Diego
Gabriela Goldberg is a PhD student in Alysson Muotri's lab at UCSD where she studies neuroimmune and glial interactions during development using human stem cell-derived brain organoids.