Stress related transcriptomic signatures of Alzheimer’s Disease
Join us for this Brain Week webinar to hear Valentina Garbarino, PhD Assistant Professor at the University of Texas, San Antonio discuss how she and her colleagues used an nCounter Custom CodeSet to probe the utility of a specific stress-related transcriptomic profile, the Conserved Transcriptional Response to Adversity (CTRA), in an early Alzheimer’s disease population. This presentation will cover the study design, methods, and analyses of the results which provide the first data to describe a blood transcriptomic signature that is susceptible to senolytic therapy in an Alzheimer’s population. Dr. Garbarino will also discuss future plans to utilize the nCounter technology to streamline analyses as the team prepares to replicate these results within larger and more diverse clinical research populations.
Valentina Garbarino, PhD
Assistant Professor, Department of Cell Systems and Anatomy, Biggs Institute for Alzheimer’s and Neurodegenerative Disease, University of Texas, San Antonio
Valentina Garbarino, PhD is an early career translational neurobiologist with formal training in the areas of the biology of aging, neuroscience, physiology and pharmacology, and translational science. As an Assistant Professor, with appointments in the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases and the Department of Cell Systems and Anatomy at the University of Texas Health Science Center, her research focus is studying the link between chronic stress and neurodegenerative disease. Her lab utilizes transcriptomic and proteomic approaches to identify and evaluate potential biomarkers for both stress and Alzheimer’s disease.