Spatial Organ Atlas: Liver
Explore the GeoMx WTA Human Liver Data
See how imaging and molecular data combine to give you a comprehensive profile of the tissue architecture and biology through this Minerva Story.
Human Liver Metadata
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Human Liver Metadata
This cohort contains 4 samples:
- Sex: Male
- Race: Asian
- Age Range: 47 years to 52 years
- BMI: Unknown
Whole Transcriptome Atlas Profiling:
- >18,000 genes
- 5μm FFPE tissue section
Profiling Strategy:
- 379 regions profiled
- Liver lobular zones (Zone 1, Zone 2, and Zone 3): (n=42, 51, 40; geometric profiling)
- Portal triad (Bile Duct, Artery and Portal Vein) (n=24, 24, 24; geometric profiling)
- Central Vein (n=25; geometric profiling)
- Kupffer cells (surrounding Portal Vein, surrounding Central Vein, and the lobular area): (n=24, 23, 24; CD68+ cell-type profiling)
- Sinusoids and Stellate cells (surrounding Portal Vein, surrounding Central Vein and the lobular area) (n=24, 23, 24; SMA+ cell type profiling)
- Fibroblasts (n=7; geometric profiling)
Morphology Markers:
- CK8/18: Hepatocytes
- CD68: Kupffer cells
- SMA: Sinusoid
- DNA: Nuclei
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