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nCounter® Myeloid Innate Immunity Panel

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Helping Your Research

The nCounter® Myeloid Innate Immunity Panel provides comprehensive coverage of myeloid-derived cells in a targeted gene expression assay. These panels can be used with multiple sample types like peripheral blood mononuclear cells (PBMCs) or formalin-fixed paraffin-embedded (FFPE) tissue sections and provide results in less than 24 hours with minimal hands-on time and data analysis.  

The Myeloid Innate Immunity Panel is designed to encompass all aspects of the innate immune response of myeloid-derived cells and can be used for basic and translational research in immuno-oncology, autoimmunity, and infectious disease. The panel is curated to include the most current and relevant genes and is available in both human and mouse versions. Use the Myeloid Innate Immunity Panel to study: 

  • Mechanisms of immune evasion
  • Damage response, wound healing & tissue repair 
  • Immune regulation 
  • Disease pathogenesis 
  • Treatment response vs. non-response
Myeloid Innate Immunity

How It Works

The nCounter Myeloid Innate Immunity Panels were developed in collaboration with leading experts in the field of immuno-oncology but can be used to study the role of myeloid-derived cells whenever the innate immune system is implicated in the response to a disease or pathogen. Each panel enables characterization of the innate immune response by profiling genes involved in the recruitment and activation of selected myeloid subtypes.

01:

770 genes In 19 different pathways and processes across 7 different myeloid cell types

02:

Rapidly analyze Complex immune responses with publication-quality results next day

03:

Optimized for difficult sample types including FFPE, PBMCs, or FACS sorted cells

04:

Genes represent all major myeloid cell types including neutrophils, eosinophils, mast cells, dendritic cells, monocytes, and macrophages with 19 functional and pathway annotations

05:

Customize with Panel Plus to spike-in up to 55 genes of your choice to tailor the panel for your research project

Panel Selection Tool

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Product Information

Specifications
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Specifications
Catalog Information

Related Resources

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Product Bulletin Myeloid Innate Immunity Panel – Product Bulletin
Poster AACR 2017 Poster_ Validation of human and mouse myeloid panels on the NanoString® nCounter® Platform

Publications

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Idelalisib inhibits experimental proliferative vitroretinopathy.

Proliferative vitreoretinopathy (PVR) is a fibrotic eye disease that develops after rhegmatogenous retinal detachment surgery and open-globe traumatic injury. Idelalisib is a specific inhibitor of phosphoinositide 3-kinase (PI3K) δ.

Comparative spatial transcriptomic and single-cell analyses of human nail units and hair follicles demonstrate transcriptional similarities between the onychodermis and follicular dermal papilla.

The nail unit and hair follicle are both hard keratin-producing organs that share various biological features. Here we used a Digital Spatial Profiling (DSP) and single cell RNA sequencing (scRNA-seq) to define a spatially resolved expression profile of the human nail unit and hair follicle.

Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.

Rationale: The incidence and sites of mucus accumulation, and molecular regulation of mucin gene expression, in COVID-19 lung disease have not been reported. Objectives: Characterize incidence of mucus accumulation and the mechanisms mediating mucin hypersecretion in COVID-19 lung disease.

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