OLD Category: Autoimmunity
September 9, 2023 / Ocul Surf
Conjunctival transcriptomics in ocular mucous membrane pemphigoid
PURPOSE: Ocular Mucous Membrane Pemphigoid (OcMMP) is an orphan disease characterized by chronic autoimmune-driven conjunctival inflammation leading to progressive scarring, debilitating symptoms, and blinding sequelae. This feasibility study aims to…
September 6, 2023 / J Pharmacol Exp Ther
Preclinical Evidence for the Glucocorticoid-Sparing Potential of a Dual Toll-Like Receptor 7/8 Inhibitor in Autoimmune Diseases
Toll-like receptor (TLR) 7 and TLR8 are single-stranded RNA-sensing endosomal pattern recognition receptors that evolved to defend against viral infections. However, aberrant TLR7/8 activation by endogenous ligands has been implicated…
October 14, 2021 / Commun Biol
Therapeutically expanded human regulatory T-cells are super-suppressive due to HIF1A induced expression of CD73
September 29, 2021 / Front Med (Lausanne)
Gene Expression Analysis in Four Dogs With Canine Pemphigus Clinical Subtypes Reveals B Cell Signatures and Immune Activation Pathways Similar to Human Disease
August 24, 2021 / J Control Release
Genetic in situ engineering of myeloid regulatory cells controls inflammation in autoimmunity
August 20, 2021 / Nat Commun
Tet2 Controls the Responses of β cells to Inflammation in Autoimmune Diabetes
July 17, 2021 / Immun Inflamm Dis
Upcoming treatments for morphea
July 7, 2021 / Kidney Res Clin Pract
Urinary exosomal microRNA profiling in type 2 diabetes patients taking dipeptidyl peptidase-4 inhibitor compared with sulfonylurea
June 14, 2021 / Int J Mol Sci
Monogenic Autoinflammatory Diseases: State of the Art and Future Perspectives
May 12, 2021 / Clin Transl Gastroenterol