OLD Category: Developmental and systems biology
November 10, 2023 / Cell Rep
Spiny projection neurons exhibit transcriptional signatures within subregions of the dorsal striatum
The dorsal striatum is organized into functional territories defined by corticostriatal inputs onto both direct and indirect spiny projection neurons (SPNs), the major cell types within the striatum. In addition…
November 2, 2023 / Front Cell Dev Biol
Core binding factor subunit β plays diverse and essential roles in the male germline
Much of the foundation for lifelong spermatogenesis is established prior to puberty, and disruptions during this developmental window negatively impact fertility long into adulthood. However, the factors that coordinate prepubertal…
November 2, 2023 / Nat Cell Biol
Regenerating human skeletal muscle forms an emerging niche in vivo to support PAX7 cells
Skeletal muscle stem and progenitor cells including those derived from human pluripotent stem cells (hPSCs) offer an avenue towards personalized therapies and readily fuse to form human–mouse myofibres in vivo.…
August 28, 2023 / Dev Cell
Defining the identity and the niches of epithelial stem cells with highly pleiotropic multilineage potency in the human thymus
Thymus is necessary for lifelong immunological tolerance and immunity. It displays a distinctive epithelial complexity and undergoes age-dependent atrophy. Nonetheless, it also retains regenerative capacity, which, if harnessed appropriately, might…
July 19, 2023 / Nature
A spatially resolved timeline of the human maternal-fetal interface
Beginning in the first trimester, fetally derived extravillous trophoblasts (EVTs) invade the uterus and remodel its spiral arteries, transforming them into large, dilated blood vessels. Several mechanisms have been proposed…
November 24, 2021 / Sci Rep
A new experimental model for the investigation of sequential hermaphroditism
November 14, 2021 / Diagnostics (Basel)
Abnormal Circulating Maternal miRNA Expression Is Associated with a Low (<4%) Cell-Free DNA Fetal Fraction
July 27, 2021 / Respir Res
Perturbation of semaphorin and VEGF signaling in ACDMPV lungs due to FOXF1 deficiency
July 21, 2021 / Nat Commun