OLD Category: gene therapy

Combination microRNA-based cellular reprogramming with paclitaxel enhances therapeutic efficacy in a relapsed and multidrug-resistant model of epithelial ovarian cancer

• Gandham SK, Mounika Rao, Aayushi Shah, Malav S. Trivedi, Mansoor M. Amiji

Chromosomal instability drives convergent and divergent evolution toward advantageous inherited traits in mammalian CHO bioproduction lineages

• Huhn S, Chang M, Kumar A, Liu R, Jiang B, Betenbaugh M, Lin H, Nyberg G, Du Z

Small but Mighty—Exosomes, Novel Intercellular Messengers in Neurodegeneration

• Kumari M, Anji A

Circulating inflammatory monocytes oppose microglia and contribute to cone cell death in retinitis pigmentosa

• Funatsu J, Yusuke Murakami, Shotaro Shimokawa, Shunji Nakatake, Kohta Fujiwara, Ayako Okita, Masatoshi Fukushima, Kensuke Shibata, Noriko Yoshida, Yoshito Koyanagi, Masato Akiyama, Shoji Notomi, Shintaro Nakao, Toshio Hisatomi, Atsunobu Takeda, Eleftherios I Paschalis, Demetrios G Vavvas, Yasuhiro Ikeda, Koh-Hei Sonoda

Nanoparticles in Clinical Translation for Cancer Therapy

• Mundekkad D, Cho WC

Reactive oxygen species reprogram macrophages to suppress antitumor immune response through the exosomal miR-155-5p/PD-L1 pathway

Nanobugs as Drugs: Bacterial Derived Nanomagnets Enhance Tumor Targeting and Oncolytic Activity of HSV-1 Virus

• Howard FHN, Al-Janabi H, Patel P, Cox K, Smith E, Vadakekolathu J, Pockley AG, Conner J, Nohl JF, Allwood DA, Collado-Rojas C, Kennerley A, Staniland S, Muthana M

BiTE secretion from in situ-programmed myeloid cells results in tumor-retained pharmacology

• Hao S, Inamdar V, Sigmund E, Zhang F, Stephan S, Watson C, Weaver S, Nielsen U, Stephan M

Multiple Treatment Cycles of Neural Stem Cell Delivered Oncolytic Adenovirus for the Treatment of Glioblastoma

• Batalla-Covello J, Ngai HW, Flores L...Lesniak MS, Aboody KS, Mooney R

Pharmacological Activation of cGAS for Cancer Immunotherapy

• Garland KM, Rosch JC, Carson CS, Wang-Bishop L, Hanna A, Sevimli S, Van Kaer C, Balko JM, Ascano M, Wilson JT

Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage

• Bedingfield SK, Colazo JM, Yu F, Liu DD, Jackson MA, Himmel LE, Cho H, Crofford LJ, Hasty KA, Duvall CL

Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs

• Lokugamage MP, Vanover D, Beyersdorf J, Hatit MZC, Rotolo L, Echeverri ES, Peck HE, Ni H, Yoon JK, Kim Y, Santangelo PJ, Dahlman JE