OLD Category: liver disease

Targeting the IGF-axis potentiates immunotherapy for pancreatic ductal adenocarcinoma liver metastases by altering the immunosuppressive microenvironment

• Hashimoto M, Konda JD, Perrino S, Fernandez MC, Lowy AM, Brodt P

A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery

• Crouchet E, Bandiera S, Fujiwara N...Fuchs BC, Hoshida Y, Baumert TF

MTL-CEBPA Combined with Immunotherapy or RFA Enhances Immunological Anti-Tumor Response in Preclinical Models

• Huang KW, Tan CP, Reebye V, Chee CE, Zacharoulis D, Habib R, Blakey DC, Rossi JJ, Habib N, Sodergren MH

Spatially Resolved Immunometabolism to Understand Infectious Disease Progression

• Tans R, Dey S, Dey NS, Calder G, O’Toole P, Kaye PM, Heeren RMA

The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis

• Torres S, Brol MJ, Magdaleno F...Byth K, Latz E, Trebicka J

Distinct Hepatic Gene-Expression Patterns of NAFLD in Patients With Obesity

• Subudhi S, Drescher HK, Dichtel LE...Miller KK, Lauer GM, Corey KE

Suppressor CD4(+) T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis

• Khamri W, Gudd C, Liu T...Weston CJ, Antoniades CG, Thursz MR

Leukocyte‐Derived High‐Mobility Group Box 1 Governs Hepatic Immune Responses to Listeria monocytogenes

• Volmari A, Foelsch K, Zierz E...Huber S, Mittruecker H, Huebener P

Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter

• Wing PA, Liu PJ, Harris JM...Protzer U, Balfe P, McKeating JA

The Role of Extracellular Vesicles as Shuttles of RNA and Their Clinical Significance as Biomarkers in Hepatocellular Carcinoma

• Costanzi E, Simioni C, Varano G, Brenna C, Conti I, Neri LM

Exploring Markers of Exhausted CD8 T Cells to Predict Response to Immune Checkpoint Inhibitor Therapy for Hepatocellular Carcinoma

• Hsu CL, Ou DL, Bai LY, Chen CW, Lin L, Huang SF, Cheng AL, Jeng YM, Hsu C

Phenotypic Characteristics of the Tumour Microenvironment in Primary and Secondary Hepatocellular Carcinoma

• Fessas P, Spina P, Boldorini RL...Akarca AU, Marafioti T, Pinato DJ