OLD Category: panels
January 4, 2024 / Front Cell Infect Microbiol
Spatial profiling of the placental chorioamniotic membranes reveals upregulation of immune checkpoint proteins during Group B Streptococcus infection in a nonhuman primate model
Background: Preterm birth is a leading cause of neonatal mortality, which is often complicated by intrauterine infection and inflammation. We have established a nonhuman primate model of Group B Streptococcus…
September 14, 2023 / Gut
Enhanced antitumour immunity following neoadjuvant chemoradiotherapy mediates a favourable prognosis in women with resected pancreatic cancer
Background: This study investigates sex disparities in clinical outcomes and tumour immune profiles in patients with pancreatic ductal adenocarcinoma (PDAC) who underwent upfront resection or resection preceded by gemcitabine-based neoadjuvant…
August 17, 2023 / Lancet
Immune response after pig-to-human kidney xenotransplantation: a multimodal phenotyping study
Background: Cross-species immunological incompatibilities have hampered pig-to-human xenotransplantation, but porcine genome engineering recently enabled the first successful experiments. However, little is known about the immune response after the transplantation of…
April 15, 2023 / Acta Neuropathol Commun
Tumor lineage-specific immune response in brain metastatic disease: opportunities for targeted immunotherapy regimen?
Metastases in the brain are the most severe and devastating complication of cancer. The incidence of brain metastasis is increasing. Therefore, the need of finding specific druggable targets for brain…
December 16, 2022 / Alzheimers Dement
INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer’s disease
November 21, 2022 / JHEP Reports
Spatial molecular and cellular determinants of STAT3 activation in liver fibrosis progression in non-alcoholic fatty liver disease
September 15, 2022 / Immunology
Transcriptomic profiling of cardiac tissues from SARS-CoV-2 patients identifies DNA damage
August 24, 2022 / Lancet Respir Med
Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study
January 24, 2022 / Cell Rep Med
System-wide transcriptome damage and tissue identity loss in COVID-19 patients
January 21, 2022 / Cancers