Category: methods

March 3, 2023 / Genome Biol

  • Zhu J, Shang L, Zhou X
Spatially resolved transcriptomics (SRT)-specific computational methods are often developed, tested, validated, and evaluated in silico using simulated data. Unfortunately, existing simulated SRT data are often poorly documented, hard to reproduce,…
March 2, 2023 / Nat Rev Genet

  • Vandereyken K, Sifrim A, Thienpont B, Voet T
The joint analysis of the genome, epigenome, transcriptome, proteome and/or metabolome from single cells is transforming our understanding of cell biology in health and disease. In less than a decade,…
February 23, 2023 / Transplantation

  • Zubair H, Azim S, Maluf DG, Mas VR, Martins PN
Solid organ transplantation saves thousands of lives suffering from end-stage diseases. Although early transplants experienced acute organ injury, medical breakthroughs, such as tissue typing, and use of immunosuppressive agents have…
February 13, 2023 / Curr Opin Organ Transplant

  • Virmani S, Rao A, Menon MC
Purpose of review: To review novel modalities for interrogating a kidney allograft biopsy to complement the current Banff schema. Recent findings: Newer approaches of Artificial Intelligence (AI), Machine Learning (ML),…
February 4, 2023 / Int J Mol Sci

  • Sheng W, Zhang C, Mohiuddin TM, Al-Rawe M, Zeppernick F, Falcone FH, Meinhold-Heerlein I, Hussain AF
Traditional immunohistochemistry (IHC) has already become an essential method of diagnosis and therapy in cancer management. However, this antibody-based technique is limited to detecting a single marker per tissue section.…
December 21, 2022 / Brief Bioinform

  • Tang Z, Zhang T, Yang B, Su J, Song Q
December 20, 2022 / Nat Rev Cardiol

  • Miranda AMA, Janbandhu V, Maatz H, Kanemaru K, Cranley J, Teichmann SA, Hübner N, Schneider MD, Harvey RP, Noseda M
December 19, 2022 / Transplantation

  • Li JSY, Raghubar AM, Matigian NA, Ng MSY, Rogers NM, Mallett AJ
December 13, 2022 / Genome Biol

  • Park J, Kim J, Lewy T, Rice CM, Elemento O, Rendeiro AF, Mason CE
December 10, 2022 / Nat Commun

  • Shen R, Liu L, Wu Z, Zhang Y, Yuan Z, Guo J, Yang F, Zhang C, Chen B, Feng W, Liu C, Guo J, Fan G, Zhang Y, Li Y, Xu X, Yao J