OLD Category: pan cancer panels
December 4, 2023 / Acta Neuropathol Commun
Glioblastoma pseudoprogression and true progression reveal spatially variable transcriptional differences
Post-resection radiologic monitoring to identify areas of new or progressive enhancement concerning for cancer recurrence is critical during patients with glioblastoma follow-up. However, treatment-related pseudoprogression presents with similar imaging features…
May 9, 2023 / Cell Death Dis
Canonical and truncated transglutaminase-2 regulate mucin-1 expression and androgen independency in prostate cancer cell lines
Androgen independency is associated with poor prostate cancer (PCa) survival. Here we report that silencing of transglutaminase-2 (TG2) expression by CRISPR-Cas9 is associated with upregulation of androgen receptor (AR) transcription…
February 8, 2023 / Cancers (Basel)
The KRAS-Mutant Consensus Molecular Subtype 3 Reveals an Immunosuppressive Tumor Microenvironment in Colorectal Cancer
Simple Summary: The poor prognosis outcome of patients with KRAS mutations (KRASmut) was correlated with an immunosuppressive tumor microenvironment (TME). At the gene expression level and pathway analysis, KRASmut tumor…
May 5, 2022 / Clin Cancer Res
CXCL14 promotes a robust brain tumor-associated immune response in glioma
November 26, 2021 / Oncoimmunology
Deep learning model enables the discovery of a novel immunotherapeutic agent regulating the kynurenine pathway
November 23, 2021 / Immun Inflamm Dis