OLD Category: toxicology
June 30, 2023 / Clin Cancer Res
Trackable Intratumor Microdosing and Spatial Profiling Provide Early Insights into Activity of Investigational Agents in the Intact Tumor Microenvironment
Purpose: Cancer drug development is currently limited by a paradigm of preclinical evaluation that does not adequately recapitulate the complexity of the intact human tumor microenvironment (TME). To overcome this,…
March 10, 2023 / Toxins
Mapping the Immune Cell Microenvironment with Spatial Profiling in Muscle Tissue Injected with the Venom of Daboia russelii
Pathological and inflammatory events in muscle after the injection of snake venoms vary in different regions of the affected tissue and at different time intervals. In order to study such…
October 28, 2021 / Mol Syst Biol
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
October 19, 2021 / Respir Res
Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
September 28, 2021 / ALTEX
A high-throughput and highly automated genotoxicity screening assay
September 23, 2021 / Sci Rep
Quantitative assessment of sensitizing potency using a dose–response adaptation of GARDskin
July 20, 2021 / Sci Total Environ
MicroRNA-based host response to toxicant exposure is influenced by the presence of gut microbial populations
July 15, 2021 / Sci Transl Med