Helping Your Research
nCounter Elements TagSets enable analysis with color-coded molecular barcodes that facilitate detection and quantitation of RNA and DNA targets by hybridizing to target-specific oligonucleotide probes. They are ideal for a range of applications requiring efficient quantitation of tens to hundreds of target molecules across a sample set, such as gene signature development and validation studies. This unique chemistry generates high-quality results from challenging sample types, such as FFPE tissue or crude cell lysates.
- Amplification-free digital counting of nucleic acids
- Compatible with FFPE, crude cell lysates, and cell lines
- Multiplex up to 228 custom targets per sample in a single tube
How it Works
nCounter Elements TagSets are flexible, off-the-shelf reagents that can be used for measuring digital counts of nucleic acid targets when used in conjunction with user-designed and -supplied target-specific oligonucleotide probes. Elements TagSets are compatible with a variety of sample sources including but not limited to formalin-fixed paraffin-embedded (FFPE) tissue, fresh frozen tissue, blood products, fine needle aspirates, cell lines, and immunoprecipitated nucleic acids.
All nCounter Elements TagSets are based on NanoString’s core technology for measuring the abundance of nucleic acids via digital detection of fluorescent molecular barcodes. However, target recognition is decoupled from the molecular barcode using intermediate probes. These probes are designed and supplied by the user.
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