Grant Opportunity: 360° View of Gene Expression Profiling in Oncology Research
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Inspired by systems biology approaches to cancer research, NanoString’s 360 Series Gene Expression Profiling Panel Collection gives you a 360° view of gene expression by combining carefully-curated content involved in the biology of the tumor, microenvironment, and the immune response into a single holistic assay. Each panel contains the 18-gene Tumor Inflammation Signature (TIS) that measures a peripherally-suppressed, adaptive immune response and has been shown to correlate with response to checkpoint inhibitors.
- PanCancer IO 360™ Panel (IO 360)
- Breast Cancer 360™ Panel (BC 360)
- Tumor Signaling 360 Panel (TS 360)
High-plex targeted gene expression analysis
Ideal for studying solid tumors, the 360 Series Panel Collection can be used to better understand the biology behind therapeutic response, therapeutic mechanism of action, immune evasion, and the interplay between the tumor and microenvironment. These panels serve as powerful tools for developing novel signatures that correlate with response and/or survival.
- 1,588 unique genes included across all panels
- PAM50, Claudin-Low, & Triple Negative Breast Cancer (TNBC) gene signatures included in the Breast Cancer 360 Panel
- Data Analysis Service for the IO 360 and Breast Cancer 360 Panels provides interactive and customizable reports with signatures scores
- Pairs with GeoMx® Cancer Transcriptome Atlas for comparative spatial RNA profiling
The Grant winner will receive:
- 24-samples worth of the IO 360, BC 360 or TS 360 panels
- Project and data analysis consultation
- NanoString reagents needed to run project
Application guidelines
- Grant Deadline: Friday, March 18th 2022
- 100-250 words recommended for Experimental Description section of application
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Terms and Conditions
Publication of Project Results:
All grant submissions are confidential to the individual submitter and will not be published or distributed, provider, however, that NanoString may share them with partners, collaborators and other third parties who are obligated to keep them confidential. Upon project completion, the grant winner agrees to participate in at least one of the following activities relating to the specific project, with specific details of the applicable activity to be mutually agreed upon in good faith by NanoString and each winner: webinar, case study, blog post, or poster presentation. Each winner agrees that NanoString shall have the right to publicly announce the winner’s name and research topic and use anonymized data from the winner’s project in application notes including in marketing materials and seminars.
Eligibility and Requirements:
Applicants must be actively enrolled or employed at an institution or company in a capacity in which they perform life science research and have the ability to ship and analyze samples within 45 days of award notification. The winner must be age 18 or older and reside in North America. Members of the immediate families of NanoString employees and directors, and/or persons living in the same household as such persons, are ineligible to participate in this grant program. NanoString will discuss in good faith with the grant winners whether the project samples will be run at a core lab facility or through the NanoString Proof of Principle laboratory. The determination will be made in NanoString’s reasonable discretion and the applicant acknowledges that, if the project is run through a core lab facility, while NanoString will provide the applicable nCounter reagents, the grant winner is responsible for any service lab charges. The grant winner will provide 4 samples to the core lab or to NanoString, as applicable, to be used with the NanoString 360 Series panel of choice.
Miscellaneous: By submitting a grant application, each applicant agrees that NanoString may use his or her name, abstract title, and abstract for marketing purposes. All grant applicants agree that NanoString may process the personal data he or she provides as part of application, including sharing such data with NanoString’s partners, collaborators and other third parties who are obligated to keep the data confidential, and in accordance with NanoString’s privacy policies available at nanostring.com/privacy. The grant award winner may be required to sign and return an affidavit of eligibility, release of liability, a publicity release, and other appropriate legal documentation reasonably requested by NanoString. No substitution or transfer of the awarded grant is allowed, except as otherwise permitted by NanoString. The award winner is responsible for any local tax liability (city, state, or federal) occurred by winning and accepting the award. If, for any reason, the grant program may not run as planned for any causes beyond the reasonable control of NanoString, then NanoString reserves the right in its sole discretion to cancel, terminate, modify or suspend the grant program. NanoString has not made any warranty, representation, or guarantee, express or implied, with respect to the grant award and related services, including, without limitation, their quality or fitness for a particular purpose. This program is void where prohibited or otherwise restricted by law. These terms and conditions and any action related to this grant program will be governed by the laws of the State of Washington without regard to or application of its conflict of law provisions or your state or country of residence. All claims, legal proceedings or litigation arising in connection with these terms and conditions and this grant program will be brought solely in the federal or state courts located in Seattle, Washington, and all applicants consent to the jurisdiction of and venue in such courts and waive any objection as to inconvenient forum. By participating in this grant program, each applicant unconditionally accepts and agrees to comply with and abide by these terms and conditions