nCounter® Fibrosis Panel

Helping Your Research

The cellular and molecular basis for fibrotic disease is still poorly understood, and the lack of biomarkers for progression and therapeutic response have hampered efforts to develop treatments. The nCounter Fibrosis Panel helps uncover the mechanisms of disease pathogenesis, identify biomarkers of progression, and develop signatures for therapeutic response. This gene expression panel combines hundreds of genes involved in the initial tissue damage response, chronic inflammation, proliferation of pro-fibrotic cells, and tissue modification that leads to fibrotic disease of the lungs, heart, liver, kidney, and skin.

How it Works

Profile 770 genes across 51 annotated pathways in human or mouse.


Study pathogenesis and identify biomarkers for fibrotic diseases of the lungs, heart, liver, kidney, and skin


Elucidate the mechanism of action behind the four stages of fibrosis: initiation, inflammation, proliferation, and modification


Understand the signaling cascade from cell stress to inflammation


Quantify the relative abundance of 14 different immune cell types

Panel Selection Tool

Find the gene expression panel for your research with easy to use panel pro

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Product Information

Coverage across Stages of Fibrosis
Functional Annotations
Product Specifications
Immune Cell Profiling
Catalog Information
Coverage across Stages of Fibrosis

Functional Annotations
Product Specifications
Immune Cell Profiling
Catalog Information

Related Resources

View All Related Resources
Product Bulletin nCounter Fibrosis Panel – Product Bulletin
Blog Post The Innovative Way Metabolic Pathways Panel is Being Used
Webinar Murine March Madness: Anatomical analysis of infection in the brain


View All Publications

Revisiting transplant immunology through the lens of single-cell technologies.

Solid organ transplantation (SOT) is the standard of care for end-stage organ disease. The most frequent complication of SOT involves allograft rejection, which may occur via T cell- and/or antibody-mediated mechanisms.

Comparative Analysis of Gene Expression in Fibroblastic Foci in Patients with Idiopathic Pulmonary Fibrosis and Pulmonary Sarcoidosis.

Background: Fibroblastic foci (FF) are characteristic features of usual interstitial pneumonia (UIP)/idiopathic pulmonary fibrosis (IPF) and one cardinal feature thought to represent a key mechanism of pathogenesis. Hence, FF have a high impact on UIP/IPF diagnosis in current guidelines.

Differential Induction of Ly6G and Ly6C Positive Myeloid Derived Suppressor Cells in Chronic Kidney and Liver Inflammation and Fibrosis.

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