nCounter® PanCancer Immune Profiling Panel

Helping Your Research

Perform multiplex gene expression analysis in human or mouse with 770 genes from different immune cell types, common checkpoint inhibitors, CT antigens, and genes covering both the adaptive and innate immune response. The panel measures many features of the immune response to facilitate rapid development of clinical actionable gene expression profiles in the context of cancer immunotherapy.

Comprehensive profiling of the immune response optimized for immuno-oncology research
Identify tumor-infiltrating lymphocytes (TILs) for the tumor microenvironment
Assess mechanistic pathway activity for single or combination studies
Customizable with up to 55 additional user-defined genes with Panel Plus option
Multi-analyte analysis with Vantage 3D™ Assays

The nCounter PanCancer Immune Profiling Panel is for cancer researchers that need more markers than is practical for RT-qPCR but don’t want the broad approach that next-gen sequencing (NGS) offers. The Panel is fully compatible with clinically relevant sample types such as fresh-frozen (FF) tissue, formalin-fixed, paraffin-embedded (FFPE) tumor sections, isolated immune cell populations such as PBMCs, and cell lysates. The panel may be used in conjunction with nCounter Panel Plus products for additional flexibility in experimental design.

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Immune Cell Type Gene Coverage

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Product Comparison

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Immune Cell Type Gene Coverage

Product Specifications

Product Comparison

360 Series Product Comparison

Fully-annotated gene lists in Excel format are available for each of the 360 Panels. The table below compares the biology coverage of the 360 Panels across the tumor, microenvironment, and the immune response to that of the PanCancer Panels Collection.

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Related Resources

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Whitepaper PanCancer Immune Profiling Advanced Analysis – Whitepaper

Product Bulletin Hallmarks of Cancer – Product Bulletin

Whitepaper Multiplexed Cancer Immune Response Analysis – Whitepaper

Publications

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Spatial and Transcriptomic Analysis of Perineural Invasion in Oral Cancer.

PURPOSE: Perineural invasion (PNI), a common occurrence in oral squamous cell carcinomas, is associated with poor survival. Consequently, these tumors are treated aggressively.

Identification and prognostic analysis of biomarkers to predict the progression of pancreatic cancer patients.

Background: Pancreatic cancer (PC) is a malignancy with a poor prognosis and high mortality. Surgical resection is the only “curative” treatment.

Sympathetic axonal sprouting induces changes in macrophage populations and protects against pancreatic cancer.

Neuronal nerve processes in the tumor microenvironment were highlighted recently. However, the origin of intra-tumoral nerves remains poorly known, in part because of technical difficulties in tracing nerve fibers via conventional histological preparations.