
nCounter® Gene Fusion Panels and CNV Assays
Helping Your Research
Increasing numbers of actionable fusions have made traditional technologies such as PCR and FISH inefficient and costly. NGS can profile multiple fusions in a single assay but is slow, complex, and expensive. Combined with direct digital counting on the nCounter® Analysis System and Junction Sequence probe design, the detection of fusion genes is highly sensitive, quantitative, and easy:
- Directly detect hundreds of fusions in one assay
- Gets results in less than 24 hours with less than 15 minutes of hands-on time
- Use challenging sample types including FFPE tissue sections
- Multiplex at the price of single-plex assays
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Product Information
The Vantage 3D™ Lung Fusion Panel includes 63 probes: 35 for specific fusion detection, 24 for positional gene expression imbalance detection, and 4 internal reference genes. Specific Lung Gene Fusion Probes detect the following gene fusion families:
Lung imbalance probes detect gene expression imbalance in the following genes:
The Vantage 3D Leukemia Fusion Panel includes 42 probes in total: 27 for specific fusion detection, 12 leukemia genes, and 3 internal reference genes.
Leukemia Gene Fusion Probes detect the following gene fusion families:
Related Resources





Publications
Distinct Signatures of Genomic Copy Number Variants Define Subgroups of Merkel Cell Carcinoma Tumors
Simple Summary: Cancer results from genetic changes in cells. These changes are often mutations that alter the DNA sequence of critical genes.
Longitudinal monitoring of circulating tumour DNA improves prognostication and relapse detection in gastroesophageal adenocarcinoma
BACKGROUND: Gastroesophageal adenocarcinoma (GOA) has poor clinical outcomes and lacks reliable blood markers. Here we present circulating tumour DNA (ctDNA) as an emerging biomarker.
Integrative genomics approach identifies molecular features associated with early-stage ovarian carcinoma histotypes
Ovarian cancer comprises multiple subtypes (clear-cell (CCC), endometrioid (EC), high-grade serous (HGSC), low-grade serous (LGSC), and mucinous carcinomas (MC)) with differing molecular and clinical behavior. However, robust histotype-specific biomarkers for clinical use have yet to be identified.
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