Masthead

nCounter®
Glial Profiling Panel

Masthead

Helping Your Research

Comprehensively study the role of astrocytes, microglia, and oligodendrocytes in health and disease with the nCounter Glial Profiling Panel. Decipher the complex interplay between glial cells, peripheral immune cells, and neurons that underlies neurodegenerative & neuroinflammatory disorders and neurotrauma such as stroke, spinal cord injury, and traumatic brain injury.

Counter Glial Profiling

How It Works

The Glial Profiling panel covers comprehensive glial cell biology involved in both homeostasis and disease and can be run on its own or paired with the Neuropathology or Neuroinflammation panels.

01:

Profile 770 human or mouse genes across 50+ pathways involved in glial cell biology:

  • Cell stress & Damage Response
  • Pathways Regulating Glia
  • Inflammation & Peripheral Immune Invasion
  • Glial Cell Homeostasis & Activation
  • Neurotransmission
02:

Quantify the relative abundance of 5 CNS cell types and 14 peripheral immune cells

03:

Customizable with Panel Plus option – add up to 55 genes of your choice

Panel Selection Tool

Find the gene expression panel for your research with easy to use panel pro

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Product Information

Functional Annotations
Cell Type Gene Coverage
Product Specifications
Catalog Information
Functional Annotations
Cell Type Gene Coverage
Product Specifications
Catalog Information

Related Resources

See All Resources
Product Bulletin Glial Panel – Product Bulletin
Flyer Glial Cell Publications – Flyer
Blog Rediscovering Microglia: Dr. Oleg Butovsky Discusses the Untapped Potential of Microglia in Neurodegenerative Diseases

Publications

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The bidirectional lung brain-axis of amyloid-β pathology: ozone dysregulates the peri-plaque microenvironment.

The mechanisms underlying how urban air pollution affects Alzheimer’s disease (AD) are largely unknown. Ozone (O3) is a reactive gas component of air pollution linked to increased AD risk, but is confined to the respiratory tract after inhalation, implicating the peripheral immune response to air pollution in AD neuropathology.

Intratarget Microdosing for Deep Phenotyping of Multiple Drug Effects in the Live Brain.

A main impediment to effective development of new therapeutics for central nervous system disorders, and for the in vivo testing of biological hypotheses in the brain, is the ability to rapidly measure the effect of novel agents and treatment combinations on the pathophysiology of native brain tissue. We have developed a miniaturized implantable microdevice (IMD) platform, optimized for direct stereotactic insertion into the brain, which enables the simultaneous measurement of multiple drug effects on the native brain tissue in situ.

Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling.

Clinical symptoms correlate with underlying neurodegenerative changes in the vast majority of people. However, an intriguing group of individuals demonstrate neuropathologic changes consistent with Alzheimer disease (AD) yet remain cognitively normal (termed “resilient”).

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