NanoString Blog

Author: Bruker Spatial Biology

CosMx SMI

Tips to optimize sample prep for highly autofluorescent samples on CosMx® SMI

The CosMx® Spatial Molecular Imager (SMI) instrument performs fluorescent imaging to read out in-situ hybridized fluorescent reporters which uniquely identify RNA transcripts. The presence of tissue autofluorescence background may reduce…

Bruker Spatial Biology / May 27, 2025
Green DNA illustration

CosMx SMI

Moving Beyond scRNA-seq: The Power of CosMx Whole Transcriptome

Single-cell RNA sequencing (scRNA-seq) has transformed molecular biology by enabling high-throughput transcriptional profiling at cellular resolution. But as powerful as scRNA-seq is, it comes with trade-offs: loss of spatial information,…

Bruker Spatial Biology / May 25, 2025

Events

Breakthroughs in Spatial Biology: AGBT 2025 Highlights

Discover the future of spatial biology! Read about our AGBT 2025 eBook featuring posters highlighting powerful new breakthroughs EpicIF, CosMx WTX, and InSituDiff, plus on-demand workshop access.

Bruker Spatial Biology / April 14, 2025
FFPE-tissues

CosMx SMI

Revealing Spatial Biology at Whole-Transcriptome Scale: Introducing the CosMx® Human Whole Transcriptome Panel

Learn how CosMx WTX brings whole-transcriptome coverage to every cell in FFPE tissues, uncovering truly groundbreaking spatial biology.

Bruker Spatial Biology / April 2, 2025
Alzheimer_brain_TMA

Neuroscience

Miranda Orr’s Spatial Analyses from Discovery to Validation Reveal Key Processes in Alzheimer’s Disease

Discover Dr. Miranda Orr’s cutting-edge spatial multiomics research in neuroscience, revealing new Alzheimer’s disease processes with advanced proteomic tools.

Bruker Spatial Biology / March 18, 2025
CosMx tissue image

CosMx SMI

Tips when performing CosMx™ data analysis with AtoMx SIP

Single-cell spatial biology opens doors to unprecedented scientific questions requiring the development of new computational workflows and approaches to analyze and interpret data. Whether you are new to single-cell spatial…

Bruker Spatial Biology / October 3, 2024