NanoString Blog

Category: GeoMx DSP

Geo location


Getting Started with Your First GeoMx® DSP Experiment: A Step-by-Step Guide

The GeoMx Digital Spatial Profiler (DSP) is a powerful tool for spatial multiomics, the in situ analysis of RNA and protein expression in tissue sections. GeoMx DSP gives you the…

Elizabeth Schneider / December 11, 2023


What does nTPM mean in the protein atlas?

The goal of the Human Protein Atlas (HPA) project is to map all human proteins in cells, tissues, and organs.  Further, it aims to annotate the function and spatial distribution of…

Nirupama Deshpande / July 3, 2023
Geo location

Digital Spatial Profiling GeoMx DSP

What is a morphology marker?

Understanding tissue morphology is crucial to identify and separate regions of tissue into meaningful biological groupings for image analysis of tissue sections. This is done using morphological markers, most of…

Nirupama Deshpande / July 2, 2023


What is immunofluorescence used for?

Immunofluorescence techniques are being increasingly used as an imaging and diagnostic tool in clinical pathology, oncology, and infectious disease, particularly for the study of biomarkers related to cancer diagnosis, prognosis,…

Nirupama Deshpande / July 1, 2023


How is immunofluorescence staining done?

Immunofluorescence (IF) staining is a widely used technique that allows for the detection and localization of antigens in any given tissue or cell type. IF methods use combinations of specific…

Nirupama Deshpande / June 28, 2023


Immunofluorescence Staining: An Overview

Immunofluorescence staining is an incredibly powerful yet simple imaging technique that optically detects the localization, distribution, and abundance of proteins at a cellular and intracellular level using fluorescent tags on…

Nirupama Deshpande / June 24, 2023
Checkpoint inhibitors


Digital Spatial Profiling

Understanding how gene expression orchestrates cellular organization within tissues is essential to gain mechanistic insights into development and disease. Spatial transcriptomics allows capturing of transcriptional activity along with positional context…

Nirupama Deshpande / June 23, 2023

Digital Spatial Profiling GeoMx DSP Spatial Transcriptomics

FFPE Genomics: a Portal Into the World of Transcriptomic Research?

The emergence of spatial transcriptomics, with its ability to generate highly detailed maps of gene expression with spatial context, is revolutionizing biomedical research, particularly in developmental biology, cancer, immunology, and…

Nirupama Deshpande / June 21, 2023

CosMx SMI GeoMx DSP Spatial Biology

Single-Cell Spatial Surpasses Single-Cell Sequencing

Modern biology research is deeply interested in discovering the fundamental mechanics that operate within an organism of interest. Since the fundamental unit of all living organisms is the cell, it…

Geoffrey Hummelke / May 11, 2023

Digital Spatial Profiling GeoMx DSP

GeoMx DSP: What’s in an ROI?

In the field of medical imaging, the region of interest (commonly abbreviated as ROI) is an area within an image that is selected for a particular purpose, including defining boundaries…

Nirupama Deshpande / March 21, 2023
Geo location

Digital Spatial Profiling GeoMx DSP

The Birth of Spatial Genomics

NanoString catalyzed the spatial biology revolution in 2019 with the launch of the GeoMx® Digital Spatial Profiler (DSP), but did you know that the beginnings of this nascent field go…

Elizabeth Schneider / February 13, 2023
Spatial Transcriptomics

GeoMx DSP Grants Spatial Transcriptomics

Standing Out in Space: Tips for Winning a Spatial Biology Grant

Nature Methods is a leading journal for molecular biologists interested in the latest and greatest life sciences research techniques. Each year since 2007, Nature Methods chooses a method to feature…

Melanie Peffer / July 25, 2022