NanoString Blog

The goal of the Human Protein Atlas (HPA) project is to map all human proteins in cells, tissues, and organs.  Further, it aims to annotate the function and spatial distribution of…

Understanding tissue morphology is crucial to identify and separate regions of tissue into meaningful biological groupings for image analysis of tissue sections. This is done using morphological markers, most of…

Immunofluorescence techniques are being increasingly used as an imaging and diagnostic tool in clinical pathology, oncology, and infectious disease, particularly for the study of biomarkers related to cancer diagnosis, prognosis,…

Immunofluorescence (IF) staining is a widely used technique that allows for the detection and localization of antigens in any given tissue or cell type. IF methods use combinations of specific…

Immunofluorescence staining is an incredibly powerful yet simple imaging technique that optically detects the localization, distribution, and abundance of proteins at a cellular and intracellular level using fluorescent tags on…

Understanding how gene expression orchestrates cellular organization within tissues is essential to gain mechanistic insights into development and disease. Spatial transcriptomics allows capturing of transcriptional activity along with positional context…

The emergence of spatial transcriptomics, with its ability to generate highly detailed maps of gene expression with spatial context, is revolutionizing biomedical research, particularly in developmental biology, cancer, immunology, and…

Modern biology research is deeply interested in discovering the fundamental mechanics that operate within an organism of interest. Since the fundamental unit of all living organisms is the cell, it…

In the field of medical imaging, the region of interest (commonly abbreviated as ROI) is an area within an image that is selected for a particular purpose, including defining boundaries…

NanoString catalyzed the spatial biology revolution in 2019 with the launch of the GeoMx® Digital Spatial Profiler (DSP), but did you know that the beginnings of this nascent field go…

Nature Methods is a leading journal for molecular biologists interested in the latest and greatest life sciences research techniques. Each year since 2007, Nature Methods chooses a method to feature…

One year for spring break, we found ourselves in Portland, Oregon. For science-y people, a trip to Portland would be incomplete without a visit to the Oregon Museum of Science…