NanoString Blog
Category: GeoMx DSP
GeoMx DSP
Getting Started with Your First GeoMx® DSP Experiment: A Step-by-Step Guide
The GeoMx Digital Spatial Profiler (DSP) is a powerful tool for spatial multiomics, the in situ analysis of RNA and protein expression in tissue sections. GeoMx DSP gives you the…
CosMx SMI GeoMx DSP
What does nTPM mean in the protein atlas?
The goal of the Human Protein Atlas (HPA) project is to map all human proteins in cells, tissues, and organs. Further, it aims to annotate the function and spatial distribution of…
Digital Spatial Profiling GeoMx DSP
What is a morphology marker?
Understanding tissue morphology is crucial to identify and separate regions of tissue into meaningful biological groupings for image analysis of tissue sections. This is done using morphological markers, most of…
GeoMx DSP
What is immunofluorescence used for?
Immunofluorescence techniques are being increasingly used as an imaging and diagnostic tool in clinical pathology, oncology, and infectious disease, particularly for the study of biomarkers related to cancer diagnosis, prognosis,…
GeoMx DSP
How is immunofluorescence staining done?
Immunofluorescence (IF) staining is a widely used technique that allows for the detection and localization of antigens in any given tissue or cell type. IF methods use combinations of specific…
GeoMx DSP
Immunofluorescence Staining: An Overview
Immunofluorescence staining is an incredibly powerful yet simple imaging technique that optically detects the localization, distribution, and abundance of proteins at a cellular and intracellular level using fluorescent tags on…
GeoMx DSP
Digital Spatial Profiling
Understanding how gene expression orchestrates cellular organization within tissues is essential to gain mechanistic insights into development and disease. Spatial transcriptomics allows capturing of transcriptional activity along with positional context…
Digital Spatial Profiling GeoMx DSP Spatial Transcriptomics
FFPE Genomics: a Portal Into the World of Transcriptomic Research?
The emergence of spatial transcriptomics, with its ability to generate highly detailed maps of gene expression with spatial context, is revolutionizing biomedical research, particularly in developmental biology, cancer, immunology, and…
CosMx SMI GeoMx DSP Spatial Biology
Single-Cell Spatial Surpasses Single-Cell Sequencing
Modern biology research is deeply interested in discovering the fundamental mechanics that operate within an organism of interest. Since the fundamental unit of all living organisms is the cell, it…
Digital Spatial Profiling GeoMx DSP
GeoMx DSP: What’s in an ROI?
In the field of medical imaging, the region of interest (commonly abbreviated as ROI) is an area within an image that is selected for a particular purpose, including defining boundaries…
Digital Spatial Profiling GeoMx DSP
The Birth of Spatial Genomics
NanoString catalyzed the spatial biology revolution in 2019 with the launch of the GeoMx® Digital Spatial Profiler (DSP), but did you know that the beginnings of this nascent field go…
GeoMx DSP Grants Spatial Transcriptomics
Standing Out in Space: Tips for Winning a Spatial Biology Grant
Nature Methods is a leading journal for molecular biologists interested in the latest and greatest life sciences research techniques. Each year since 2007, Nature Methods chooses a method to feature…