NanoString Blog
Category: Immunology
Immunology nCounter Oncology
TIS GEP: Use Cases in Sample Stratification, Assessment of Treatment Effect, and as a Component of a Multivariate Biomarker
Introduction to the TIS Gene Expression Profile Innovations in multiplex gene expression analysis are revolutionizing translational research and clinical practices by enabling identification of gene signatures involved in various biological…
Immunology Infectious Disease Oncology
T-Cell Receptor Diversity…What Are You Missing?
The T cell receptor (TCR) is one of the distinguishing molecules of the adaptive immune system. TCRs allow mammalian immune systems to recognize and respond to foreign entities (pathogens, vaccines,…
Immunology Infectious Disease nCounter
How NanoString nCounter® helps vaccine research: Part 2, A tale of three viruses
In the first part of this two-part blog series, I discussed NanoString nCounter® technology. nCounter allows biologists to quantify gene expression using a series of molecular probes. One application of…
Immunology Infectious Disease nCounter
How nCounter helps vaccine research: Part 1, Improving Vaccines
I really dislike needles. In fact, I’m downright needle-phobic. When I was notified of my eligibility to receive my COVID-19 vaccine, it was without a doubt the most excited I…
Immunology Infectious Disease
COVID-19 Pathogenesis Steps Out of the Shadows
“Analysis of pulmonary vessels showed that widespread thrombosis with microangiopathy ─ a severe condition wherein small blood clots are formed within the tiniest of blood vessels ─ was 9x more…
Immunology Oncology
Why is Spatial Transcriptomics Critical to Studying Sarcomas? Q&A with Dr. Troy McEachron, Ph.D
“Whereas the EWS specimens tended to have very simple genomes, the osteosarcoma specimens looked like a hand grenade had gone off in the genome. These were the most fragmented and…
Autoimmunity Immunology
How to Resolve the Complexity of Autoimmune Diseases
What are Autoimmune Diseases? Autoimmune diseases are chronic inflammatory conditions, life-long debilitating illnesses with increased mortality, and high healthcare costs for therapy and care. They are systemic conditions characterized by…
Autoimmunity Immunology
Q&A with Dr. Oliver Brain: Unintended Consequences Create a Unique Opportunity to Study Inflammatory Bowel Disease.
Oliver Brain, MRCP, PhD, is a principal investigator at the University of Oxford, Nuffield Department of Clinical Medicine, and a recent winner of an nCounter® Autoimmune Profiling Panel through a…