NanoString Blog

Category: Digital Spatial Profiling

Digital Spatial Profiling GeoMx DSP

GeoMx DSP: What’s in an ROI?

In the field of medical imaging, the region of interest (commonly abbreviated as ROI) is an area within an image that is selected for a particular purpose, including defining boundaries…

Nirupama Deshpande / March 21, 2023
Geo location

Digital Spatial Profiling GeoMx DSP

The Birth of Spatial Genomics

NanoString catalyzed the spatial biology revolution in 2019 with the launch of the GeoMx® Digital Spatial Profiler (DSP), but did you know that the beginnings of this nascent field go…

Nadine Bedford / February 13, 2023
Spatial Transcriptomics

Digital Spatial Profiling Multiomics Spatial Analysis Spatial Transcriptomics

Spatial Multiomics Identifies New Actionable Therapeutic Targets

Pancreatic cancer represents 3% of the overall cancers in America and yet is responsible for 7% of all cancer deaths. The five-year relative survival rate – the cancer-related death rate…

Laura Tabellini Pierre / October 4, 2022

Digital Spatial Profiling GeoMx DSP Spatial Transcriptomics

A new map for our anatomy: the Spatial Organ Atlas

One year for spring break, we found ourselves in Portland, Oregon. For science-y people, a trip to Portland would be incomplete without a visit to the Oregon Museum of Science…

Melanie Peffer / June 13, 2022
Rendering of oncology proteins

Digital Spatial Profiling GeoMx DSP nCounter Oncology Spatial Transcriptomics

New approaches to CAR-T therapy

What is CAR-T cell therapy? In the fight against cancer, immunotherapies that enlist and strengthen the power of a patient’s immune system to attack tumor cells have revolutionized treatment paradigms.…

Nirupama Deshpande / January 18, 2022
3d model of a neuron

Digital Spatial Profiling nCounter Neuroscience Spatial Transcriptomics

Neurodegenerative disorders and Parkinson’s disease.

The idiom “to lose one’s nerves” is literally true when it comes to neurodegenerative disorders. These disorders are characterized by the progressive loss of disease-specific neural populations in the brain…

Nirupama Deshpande / December 6, 2021

Digital Spatial Profiling Spatial Biology

The Importance of Segmentation in Spatial Biology

In a highly interconnected world, clear communication and information across the globe are critical. The same is true at the tissue and cellular levels. Cells communicate through chemical signals such…

Laura Tabellini Pierre / October 29, 2021
Spatial Transcriptomics

Digital Spatial Profiling GeoMx DSP Spatial Biology Spatial Transcriptomics

Spatial Transcriptomics: Birth of GeoMx® Digital Spatial Profiler

“A rose started off a bud, a bird started off an egg, and a forest started off a seed.” (Matshona Dhliwayo, author and philosopher). It may seem odd, but the…

Laura Tabellini Pierre / May 24, 2021
Spatial Transcriptomics

Digital Spatial Profiling GeoMx DSP Spatial Biology

Why Spatial Biology Enhances Spatial Transcriptomics Data

Spatial Transcriptomics is used to determine subcellular localization of mRNA molecules. NanoString explains how this data enhances research.

Laura Tabellini Pierre / April 10, 2021
Spatial Transcriptomics

Digital Spatial Profiling GeoMx DSP Spatial Biology Spatial Molecular Imaging Spatial Transcriptomics

Spatial Biology named Method of the Year by Nature Methods

Established in 2007, the Nature Methods’ “Method of Year” feature has covered the most revolutionary methodological developments in life science research.   Starting in 2007, the Method of Year winner was,…

Karrie Spitzer / March 29, 2021
Coffee blue background

Digital Spatial Profiling Q&A Services and Core Labs

Excellence, Cooperation, and Passion Come Together to Serve the Scientific Community: Q&A with Dr. Peter O’Toole, University of York

Dr. Peter O’Toole, Ph.D., is the director of the Bioscience Technology Facility at the University of York in England, where he established and still leads the Imaging and Cytometry Laboratory, one of the…

Laura Tabellini Pierre / August 3, 2020
Checkpoint inhibitors

Digital Spatial Profiling Q&A

Q&A with Dr. Aubrey Thompson, Ph.D.: The GeoMx® Digital Spatial Profiler is Turning the Tables on Breast Cancer

E. Aubrey Thompson, Ph.D is a Professor in the Department of Cancer Biology at the Mayo Clinic in Jacksonville, FL. His research focuses on breast cancer and using genomic and…

Laura Tabellini Pierre / April 27, 2020