NanoString Blog
Author: NanoString
CosMx SMI
Tips When Generating Single-Cell Spatial Data: Sample Selection
We are excited to share the second installment of tips for successful CosMx™ SMI single-cell spatial runs at 1000-plex. Our first installment of tips focused on data by tissue and…
CosMx SMI
Top 3 Tips for Successful CosMx™ SMI Single-cell Spatial Runs at 1000 plex
We are excited to share insights and recommendations to enhance your experience with CosMx™ SMI 1000-plex RNA assays. The quality of single-cell spatial data is influenced by various factors, and…
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Common questions in molecular biology: What is a cell counter called?
There are several types of cell counters that go by different names, usually named after their uses or type of cell counting method. Hemocytometers The original cell counters are known…
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Common questions in molecular biology: What are the advantages of DNA barcoding?
DNA barcoding is a method of identification based on DNA sequences made feasible by available genomic sequence data. Initially developed as a tool for rapid species identification (Hebert), DNA barcodes consist…
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Common questions in molecular biology: What is an example of an oligonucleotide?
Oligonucleotides, short polymers of the nucleotide building blocks of nucleic acids such as DNA or RNA, come in many forms. In nature, oligonucleotides exist mainly as small non-coding RNAs such as…
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Common questions in molecular biology: What is DNA barcoding and why is it important?
DNA barcoding is used in two similar yet divergent ways in biology. While important to different areas of biology, both are modeled on the concept of the Universal Product Codes…
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Common questions in molecular biology: How many types of cell counters are there?
Although it appears to be a simple question, there are several answers to “how many types of cell counters are there?” depending on how the word “type” is defined. Defining…
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Common questions in molecular biology: What are the advantages of cell counters?
Cells, the basic unit of life, are microscopic, making their identification a challenge. Cell biologists in particular often require an accurate assessment of the specific cell types present in an experiment.…
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Common questions in molecular biology: How is DNA barcoding used in research?
The term DNA barcoding is used in two ways in research. The original use was based on the discovery of a short, standardized genetic region found in fish to have a…
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Common questions in molecular biology: Why is it called DNA barcoding?
DNA barcoding was named for its conceptual similarity to the Universal Product Codes (UPCs) used by supermarkets and other retailers to distinguish commercial products via a unique digital code. Based…
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Why Oligonucleotides Are Critical Components of DNA and RNA Expression Research
With all the advances in molecular biology over the last several decades, one of the most consistently used tools is the oligonucleotide. Oligonucleotides are relatively short (oligo) single-stranded sequences of…
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How DNA Barcoding Improves Gene Expression Analysis and Biomarker Discovery
The phrase “DNA barcoding” can be applied to several methods of using unique DNA sequences for identification purposes. Sometimes known as “molecular barcoding,” DNA barcoding describes the use of unique…