NanoString Blog
Digital Spatial Profiling
Q&A with Dr. Aubrey Thompson, Ph.D.: The GeoMx® Digital Spatial Profiler is Turning the Tables on Breast Cancer
E. Aubrey Thompson, Ph.D is a Professor in the Department of Cancer Biology at the Mayo Clinic in Jacksonville, FL. His research focuses on breast cancer and using genomic and…
Digital Spatial Profiling Miscellaneous
Stories of Remarkable Technological Advances at AGBT 2020
The Advances in Genome Biology and Technology conference celebrated its 20th-anniversary event this February, and what a dramatic range of advances have occurred in our field since the first meeting!…
Grants nCounter
The Innovative Way Metabolic Pathways Panel is Being Used
Liver disease encompasses multiple conditions preventing the liver from functioning. These conditions are often associated with altered metabolic pathways including altered glucose and lipid metabolism. in 2019 NanoString® awarded a…
Autoimmunity Digital Spatial Profiling Neuroscience Oncology
Readers’ Favorite Webinars: A Year in Review
NanoString webinars allow you to sit back, relax and listen to a leader in the field talk about his/her research and/or answer your questions. They have always been a crowd-pleaser,…
Digital Spatial Profiling
Redefining Precision: Why Spatial Resolution Matters
Functional annotation of gene and protein expression is a crucial step in deciphering cellular mechanisms. Traditional transcriptomic and proteomic assays are done in bulk, where RNA and proteins from different…
Neuroscience
Of Inflammasome and Tauopathies in Mice and Men
Tauopathies are a class of neurodegenerative diseases characterized by the aggregation of tau proteins in neurofibrillary tangles in the human brain. These proteins are associated to microtubules and are found…
Digital Spatial Profiling Miscellaneous
SITC 2019 may be over, but the era of Spatial Genomics enabled by the GeoMx Digital Spatial Profiler has just begun.
The curtains have fallen on SITC 2019—the 34th annual meeting organized by the Society for Immunotherapy of Cancer—but excitement amongst the participants remains high after five days of knowledge exchange…
Oncology
Immunotherapy in Tumors: Integrated Information to Outsmart Cancer
If it wasn’t such a devastating disease, there would be memes about how super-smart cancer is. Cancer cells can express neoantigens — tumor-specific, mutated peptides — that, when processed and…
Digital Spatial Profiling
Spatial Profiling using the GeoMx RNA Assay for NGS Readout: Robust Technology for Identification of Novel Biomarkers and Early Detection of Melanoma
Early diagnosis of melanoma is critical for improved clinical outcomes and survival of patients. Yet disagreement in traditional histology-based diagnosis frequently occurs. Despite currently available molecular technologies, melanomas characterized by…
Oncology
A Transcriptomic Solution Customized for Your Every Need
The flexibility of the NanoString nCounter® platform has been designed to accommodate a wide range of organisms, molecular targets, and sample inputs. Researchers can request “made-to-order” Custom CodeSets for up…
Digital Spatial Profiling Miscellaneous Oncology
Meet NanoString Scientists at the AMP 2019 Annual Meeting & Expo
When Elaine Lyon, Ph.D., a scientist on the board of the Association for Molecular Pathology (AMP) was asked why she is involved with AMP, its activities and initiatives, she quoted…
Oncology
Top Challenges of Biofluid Samples when Profiling FFPE miRNA Biomarkers
In 1993, Dr. Victor Ambros’ lab discovered a small RNA sequence, Lin-4, that was “essential for the normal temporal control of diverse postembryonic developmental events in C. Elegans”. Sequence analysis…