nForm Blog
A discussion on advances in biomarker research
nCounter
Gene Expression Profiling Made Easy: The Birth of nCounter®
Nanostring: noun; a piece of DNA (probe) attached to a linear sequence of fluorophores made up of four different colors (barcode). Each probe is complementary to a unique target oligonucleotide.…
GeoMx Q&A
GeoMxユーザーインタビュー
岡山大学病院ゲノム医療総合推進センターの遠西大輔先生に、ご研究やバイオバンクプロジェクト、さらにがん研究での空間発現解析のポテンシャルなどを伺いました。 空間プロファイリングのデータで得られた知見を、臨床で利用できる簡単なアッセイに落とし込みたい。
Digital Spatial Profiling nCounter Oncology
New approaches to CAR-T therapy
What is CAR-T cell therapy? In the fight against cancer, immunotherapies that enlist and strengthen the power of a patient’s immune system to attack tumor cells have revolutionized treatment paradigms.…
Neuroscience Publication Watch Spatial Biology
The Neuroinflammatory Puzzle of the Autoimmune Disease Multiple Sclerosis
What is Multiple Sclerosis? In 1868, a German physician Leopold Ordenstein and his mentor Jean-Martin Charcot, published a work that fundamentally changed our understanding of the disease Multiple Sclerosis1. For…
Digital Spatial Profiling nCounter Neuroscience Spatial Transcriptomics
Neurodegenerative disorders and Parkinson’s disease.
The idiom “to lose one’s nerves” is literally true when it comes to neurodegenerative disorders. These disorders are characterized by the progressive loss of disease-specific neural populations in the brain…
nCounter Neuroscience Spatial Transcriptomics
Alzheimer’s Disease Pathology: Fear, Confusion, and the Search for a Cure
Alzheimer’s disease pathology: a short sentence loaded with fear, confusion, and incredulity. The word “Alzheimer’s” first appeared in a German psychiatry handbook called “General Psychiatry” on July 15, 1910. This…
Immunology Infectious Disease Oncology Publication Watch
T-Cell Receptor Diversity…What Are You Missing?
The T cell receptor (TCR) is one of the distinguishing molecules of the adaptive immune system. TCRs allow mammalian immune systems to recognize and respond to foreign entities (pathogens, vaccines,…
Data Analysis GeoScript Hub Q&A
The Inspiration Behind GeoScript™ Hub for Spatial Data Analysis
Meet two of NanoString’s finest, Debra Toburen, Senior Director of Software Product Management, and Prajan Divakar, Senior Product Enablement Scientist, who are focused on enabling customers to get the most…
Digital Spatial Profiling Spatial Biology
The Importance of Segmentation in Spatial Biology
In a highly interconnected world, clear communication and information across the globe are critical. The same is true at the tissue and cellular levels. Cells communicate through chemical signals such…
Grants nCounter Q&A
NanoString People of Color and Allies (nPOCA) ERG Grant Support Program
2020 will be remembered as the year that a novel viral pandemic and the protests galvanized by the death of George Floyd disrupted modern society. These events, while seemingly unrelated,…
GeoMx Oncology
Breast Cancer: Best practices for using GeoMx® Digital Spatial Profiler
It’s October and breast cancer awareness month. Breast cancer kills more women than any other type of cancer. It isn’t just limited to women either – a man’s lifetime breast…
Immunology Infectious Disease nCounter
How NanoString nCounter® helps vaccine research: Part 2, A tale of three viruses
In the first part of this two-part blog series, I discussed NanoString nCounter® technology. nCounter allows biologists to quantify gene expression using a series of molecular probes. One application of…