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nForm Blog

A discussion on advances in biomarker research

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nCounter

Gene Expression Profiling Made Easy: The Birth of nCounter®

Nanostring: noun; a piece of DNA (probe) attached to a linear sequence of fluorophores made up of four different colors (barcode). Each probe is complementary to a unique target oligonucleotide.…

Laura Tabellini Pierre / January 31, 2022
Geo location

GeoMx Q&A

GeoMxユーザーインタビュー

岡山大学病院ゲノム医療総合推進センターの遠西大輔先生に、ご研究やバイオバンクプロジェクト、さらにがん研究での空間発現解析のポテンシャルなどを伺いました。 空間プロファイリングのデータで得られた知見を、臨床で利用できる簡単なアッセイに落とし込みたい。

Fumiyo Kurokawa / January 21, 2022
Rendering of oncology proteins

Digital Spatial Profiling nCounter Oncology

New approaches to CAR-T therapy

What is CAR-T cell therapy? In the fight against cancer, immunotherapies that enlist and strengthen the power of a patient’s immune system to attack tumor cells have revolutionized treatment paradigms.…

Nirupama Deshpande / January 18, 2022

Neuroscience Publication Watch Spatial Biology

The Neuroinflammatory Puzzle of the Autoimmune Disease Multiple Sclerosis

What is Multiple Sclerosis? In 1868, a German physician Leopold Ordenstein and his mentor Jean-Martin Charcot, published a work that fundamentally changed our understanding of the disease Multiple Sclerosis1. For…

Nirupama Deshpande / December 22, 2021
3d model of a neuron

Digital Spatial Profiling nCounter Neuroscience Spatial Transcriptomics

Neurodegenerative disorders and Parkinson’s disease.

The idiom “to lose one’s nerves” is literally true when it comes to neurodegenerative disorders. These disorders are characterized by the progressive loss of disease-specific neural populations in the brain…

Nirupama Deshpande / December 6, 2021

nCounter Neuroscience Spatial Transcriptomics

Alzheimer’s Disease Pathology: Fear, Confusion, and the Search for a Cure

Alzheimer’s disease pathology: a short sentence loaded with fear, confusion, and incredulity. The word “Alzheimer’s” first appeared in a German psychiatry handbook called “General Psychiatry” on July 15, 1910. This…

Nirupama Deshpande / November 22, 2021

Immunology Infectious Disease Oncology Publication Watch

T-Cell Receptor Diversity…What Are You Missing?

The T cell receptor (TCR) is one of the distinguishing molecules of the adaptive immune system. TCRs allow mammalian immune systems to recognize and respond to foreign entities (pathogens, vaccines,…

Trena Cormier / November 15, 2021

Data Analysis GeoScript Hub Q&A

The Inspiration Behind GeoScript™ Hub for Spatial Data Analysis

Meet two of NanoString’s finest, Debra Toburen, Senior Director of Software Product Management, and Prajan Divakar, Senior Product Enablement Scientist, who are focused on enabling customers to get the most…

Sue Giske / November 8, 2021

Digital Spatial Profiling Spatial Biology

The Importance of Segmentation in Spatial Biology

In a highly interconnected world, clear communication and information across the globe are critical. The same is true at the tissue and cellular levels. Cells communicate through chemical signals such…

Laura Tabellini Pierre / October 29, 2021

Grants nCounter Q&A

NanoString People of Color and Allies (nPOCA) ERG Grant Support Program

2020 will be remembered as the year that a novel viral pandemic and the protests galvanized by the death of George Floyd disrupted modern society. These events, while seemingly unrelated,…

Trena Cormier / October 24, 2021
Breast cancer rendering

GeoMx Oncology

Breast Cancer: Best practices for using GeoMx® Digital Spatial Profiler

It’s October and breast cancer awareness month. Breast cancer kills more women than any other type of cancer. It isn’t just limited to women either – a man’s lifetime breast…

Melanie Peffer / October 15, 2021

Immunology Infectious Disease nCounter

How NanoString nCounter® helps vaccine research: Part 2, A tale of three viruses

In the first part of this two-part blog series, I discussed NanoString nCounter® technology. nCounter allows biologists to quantify gene expression using a series of molecular probes. One application of…

Melanie Peffer / October 5, 2021